50 citations
,
September 2014 in “Stem cell reports” In this study, BLIMP1 was found to function in terminally differentiated epidermal cells to maintain homeostasis, rather than defining a sebocyte progenitor population.
76 citations
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June 2015 in “Journal of biomedical science” This study demonstrated that dominant mutations in mouse gasdermin A3 disrupt mitochondrial oxidative stress regulation, suggesting a gain-of-function effect on epidermal differentiation.
5 citations
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September 2015 in “BMC Medical Genetics” In this study, individuals with a c.1072C > T mutation in the EDAR gene showed more hair shaft deformations compared to non-mutation carriers, highlighting EDAR's role in hair follicle development.
January 2025 in “Nanoscale” This study reports that a new boron/nitrogen-doped carbon nano-onion-based delivery system for doxorubicin enhanced its uptake and anticancer effects in specific cancer cell types, while reducing cardiotoxicity in human heart cells.
August 2015 in “MOJ proteomics & bioinformatics” This study suggests that epithelial-derived pop-up keratinocytes (ePUKs) may improve regenerative medicine applications due to their specific phenotype and increased expression of proteins involved in regulating cellular movement and wound healing.
May 2025 in “Cellular Oncology” This study suggests that dual inhibition of P-cadherin and c-Met could be an effective treatment strategy for head and neck squamous cell carcinoma by targeting resistant tumor cells.
September 2025 in “Molecules” This study found that Camellia oleifera leaf extracts, especially the 50% ethanolic extract, have significant antioxidant activity and may offer promising bioactive compounds for cosmetic and pharmaceutical uses.
January 2025 in “JCEM Case Reports” In this case report, researchers described a patient with Cushing's Disease exhibiting no detectable mass, where Metyrapone therapy was effectively used to manage symptoms, suggesting a treatment option for similar diagnostic challenges.
December 2009 in “Pediatrics in review” This case study describes a 17-year-old girl initially thought to be experiencing a Crohn disease exacerbation, but ultimately found to have a trichobezoar causing small bowel obstruction.
April 2026 in “Clinical Case Reports” This case study suggests that "celiac hepatitis" should be considered in patients with unexplained liver dysfunction, highlighting the importance of recognizing celiac disease to avoid misdiagnosis and allow reversal of liver abnormalities with proper treatment.
4 citations
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February 2021 in “Zenodo (CERN European Organization for Nuclear Research)” This study measured heavy metal concentrations in Hibiscus rosa-sinensis, Eclipta alba, and Solanum nigrum, finding that levels for Cu, Cr, Cd, Hg, As, and Pb were within WHO safe limits, suggesting these medicinal plant extracts are free from heavy metal toxicity concerns.
17 citations
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January 2021 in “Agrobiological Records” This study reported that allethrin caused dose-dependent toxico-pathological effects, including decreased feed intake, body weight, and blood parameters, and organ damage in adult male albino rats.
1 citations
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August 2022 in “International journal of biological and chemical sciences” This study found that iodine deficiency, iodine excess, or the presence of antithyroid substances affected growth and behavior in Wistar rats, leading to various symptoms such as lethargy and alopecia.
17 citations
,
August 2012 in “Journal of Medical Genetics” This article reviews the genetic mutations associated with hypohidrotic ectodermal dysplasia and reports no new clinical results; the authors highlight the roles of EDA gene isoforms and related receptors.
1 citations
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November 2022 in “Anais Brasileiros de Dermatologia” This study found that hospitalized pediatric COVID-19 patients frequently display skin, mucosal, and nail manifestations, particularly periorbital erythema and edema, and the authors suggest COVID-19 be considered among childhood viral exanthem rashes.
1 citations
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December 2019 in “The Professional Medical Journal” This study concluded that psoriasis and dermatitis herpetiformis are prevalent in celiac disease patients, while vitiligo is rare, highlighting the importance of routine screening for autoimmune skin manifestations.
16 citations
,
January 2010 in “Indian Journal of Dermatology, Venereology and Leprology” This review discusses the role of skin manifestations as early markers and prognostic indicators of HIV infection in children but reports no new clinical results.
July 2025 in “Ecotoxicology and Environmental Safety” This study found that higher levels of lead and molybdenum in hair were associated with an increased risk of dyslipidemia, while there was a significant interaction showing opposing effects of lead and cadmium on dyslipidemia risk among adults in China.
This study identified a high proportion of dual TCR Treg cells in both lymphoid and non-lymphoid tissues of mice, revealing their tissue specificity, TCR repertoire characteristics, and functional phenotypes.
95 citations
,
January 2007 in “Human biology” This study proposes a new, objective method to classify human hair into eight categories based on specific shape measurements, rather than traditional ethnicity-based classifications.
6 citations
,
January 2018 in “Journal of Cellular Physiology” In this study, adipose-derived stem cells from human scalp were successfully directed towards chondrocyte differentiation, with TGF-beta3 and BMP-6 growth factors proving effective for in vitro chondrogenesis.
April 2015 in “The FASEB Journal” In this study, NM exposure in mouse skin disrupted pilosebaceous units, initially decreasing markers of sebum production and cellular division, but showed signs of healing and marker recovery by day five.
286 citations
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August 2007 in “Journal of Clinical Investigation” This review examines the interplay of genetics and neuroimmunology in alopecia areata, highlighting its potential to inform broader autoimmunity research, but reports no new findings.
151 citations
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February 2006 in “Stem Cells and Development” This study found that hair follicle-derived dermal stem cells and bone marrow mesenchymal stem cells have similar growth, differentiation capabilities, and surface marker expressions, suggesting hair follicles could be accessible sources for mesenchymal stem cells.
32 citations
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May 2012 in “PloS one” This study found that despite the persistence of aberrant double-negative T-cells, functional immune-competence was maintained after thymic transplantation in a patient with a rare FOXN1 mutation.
15 citations
,
July 2004 in “AIDS” This case report describes a black HIV-2 patient who experienced reversible nail, hair, and skin hyperpigmentation linked to ritonavir-boosted indinavir therapy, which resolved after discontinuation.
3 citations
,
October 2025 in “Journal of Materials Science Materials in Medicine” This review discusses various biomedical applications of hyaluronic acid, highlighting its roles in cancer treatment, wound healing, inflammation control, antibiotics, and antioxidant functions, with an emphasis on recent developments and potential for advanced drug delivery and tissue repair systems.
2 citations
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March 2018 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that both bFGF and herbal extracts significantly induced proliferation in human hair follicle mesenchymal stem cells, suggesting their potential for promoting hair growth.
1 citations
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October 2023 in “European Journal of Dermatology” This study found that combining hair transplantation with platelet-rich plasma treatment significantly improved hair regeneration, reduced hair loss, and minimized skin lesion areas in patients with androgenic alopecia compared to hair transplantation alone, suggesting enhanced treatment efficacy.
This article hypothesizes that thymoma with aplastic anemia may result from abnormal autoimmune CD8+ T lymphocytes produced by the thymoma, potentially leading to other cytotoxic T-cell-mediated autoimmune diseases.