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This study analyzed blood samples from individuals with alopecia areata and found that NKG2D+ immune cells, particularly memory-like NK cells, may better correlate with disease activity compared to CD8+ cells, though significant variability among individuals complicates these findings.

People with acne have more CD4+ immune cells in their skin than healthy people.

This study developed an animal model that recreates alopecia areata by injecting healthy human skin grafts in immunocompromised mice with peripheral blood mononuclear cells enriched for NKG2D+ and CD56+ cells.

In this study, researchers developed a new humanized mouse model for alopecia areata that highlights the role of specific immune cells and may aid in discovering new treatments for the disease.

This review examines the diversity and role of stem cells in the adult dermis, noting a lack of precise understanding about their hierarchy and relationship to dermal fibroblast subpopulations, and reports no new results.

This study explored peripheral blood immune dysregulation in alopecia areata through single-cell analyses, identifying systemic changes linked to disease severity and key signaling roles for monocytes, NK cells, and memory T cells, suggesting potential therapeutic targets.

This study introduces stem cell activity as a key factor influencing the effects of IFN-γ and TGF-β1 on autoimmune disease dynamics, showing that varying cytokine levels can modulate stem cell activity and immune privilege, impacting tissue regeneration and disease flares.

This study found that FOXN1 haploinsufficiency is a significant genetic factor causing T cell lymphopenia at birth, linked to reduced thymic function in both humans and mice.

In this study, human dermal fibroblasts were identified as natural host cells that support productive Merkel cell polyomavirus infection, and the MEK antagonist trametinib was introduced as an effective inhibitor to control the virus.

This review discusses the role of the TCL1 transgenic mouse model in understanding chronic lymphocytic leukemia biology and highlights the importance of exploring new pathogenetic and therapeutic targets.

This study identified specific markers that can distinguish between stem cells in different regions of human scalp hair follicles, offering potential strategies for cell sorting and purification based on these markers.

This study found that 5% primed conditioned medium from human umbilical cord blood-derived mesenchymal stromal cells significantly improved hair density, thickness, and growth rate in patients with androgenetic alopecia.

This review discusses the potential of adipose-derived stem cells for treating vitiligo, hair loss, and chronic wound healing, but reports no new clinical results and suggests the need for further investigation.

This study found that basal cell carcinoma cells differentiate along hair follicle lineages and may be influenced by hair follicle cycle modulators for potential therapeutic targeting.

This review discusses the roles and characteristics of skin stem cells, their niches, and signaling pathways in skin maintenance, aging, and cancer, highlighting their potential in therapeutic applications but presenting no new clinical findings.

This case report describes a 69-year-old woman with hirsutism and elevated serum testosterone, where surgery resolved symptoms and serum testosterone, suggesting ovarian steroid cell tumor consideration in similar profiles.

This case report describes a patient with primary cutaneous natural killer/T-cell lymphoma, nasal type, where monoclonal Epstein–Barr virus genome expansion was associated with terminal aggressive behavior after an indolent clinical course.

This report presents a case where a patient with Omenn syndrome, complicated by cytomegalovirus infection, was successfully treated using reduced intensity conditioning allogeneic HSCT from a sibling donor.

This study reports that a new protocol using Angio PRP improved wound healing in mice by enhancing key healing processes and regulating inflammation, suggesting potential for clinical advancements.

This review discusses the potential of adipose-derived stem cells for regenerative medicine, highlighting their ability to differentiate, secrete factors, and modulate the immune response, but reports no new findings.

This review examines the role of innate lymphoid cells in allergic diseases and the influence of an allergic microenvironment on their plasticity, without reporting new clinical outcomes.

This study found that human platelet lysate supported mesenchymal stem cell growth as effectively as fetal bovine serum, while fetal bovine serum was more effective for hepatocyte proliferation.

This case report highlights a rare instance of postmenopausal virilization in a 71-year-old woman due to coexisting ovarian hilus cell hyperplasia and a Sertoli-Leydig cell tumor.

This study reports a case of a 28-year-old woman diagnosed with metastatic breast cancer through bone marrow analysis using flow cytometry and immunohistochemistry, highlighting the potential of flow cytometry as a valuable diagnostic tool for detecting solid tumors.

In this study, researchers identified six novel prognostic biomarkers for bladder cancer and developed a predictive model that effectively stratifies patients into high-risk and low-risk groups based on immune cell infiltration differences and gene expression.

This review discusses the potential of adipose-derived tissue components like nanofat and stem cells for aesthetic rejuvenation, covering their use in hair growth, scar reduction, and more, without reporting new clinical results.

This review highlights recent insights into how IL-15 influences T cell responses and contributes to immunopathogenesis in various diseases, suggesting its crucial role in TCR-independent activation and potential in optimizing therapeutic strategies.

This case report highlights that in postmenopausal women with severe hyperandrogenism, thorough adrenal and pelvic evaluations, hormonal profiling, and permanent pathology are essential for accurate diagnosis and management of androgen-secreting tumors, such as AGCTs, to prevent misdiagnosis and ensure effective treatment.

This study examines the role of immune phenotypes and cytokines in the development of pathological scars, providing insights that may aid in early identification and treatment strategies for these scars.

This case report describes a 24-year-old woman with a stage IIIC retiform variant of Sertoli-Leydig cell tumour, highlighting the challenges in managing this rare ovarian tumour.