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AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Topical contact sensitizers can treat certain skin conditions but are rarely used in the U.K.

Transgender patients need proper skin care, especially when undergoing hormone treatments, to manage issues like acne and hair loss.

Blocking IL-12/IL-23 does not help with hair loss in alopecia areata for mice or humans.

The document concludes that computational models are useful for understanding immune responses and could improve cancer immunotherapy.

JAK inhibitors may soon be a safe and effective treatment for alopecia areata.

Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.

Old treatments for other skin conditions showed promise for hair regrowth in mice with a hair loss condition.

Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.

Immune checkpoint inhibitors can cause skin issues but are linked to better cancer outcomes.

Special immune cells called Treg cells are important for maintaining and regenerating hair by activating a specific growth signal in hair stem cells.

AHCC reduces hair loss and liver injury caused by chemotherapy in rodents.

Low-Level Laser Therapy and other light treatments for hair growth lack strong evidence and need more research.

A Brazilian teenager with severe hair loss had total hair regrowth with no side effects after using tofacitinib.

Calcipotriol works almost as well as clobetasol for mild to moderate alopecia areata with fewer side effects.

HSP90 and lamin A/C are crucial for hair growth and could be targets for treating hair loss.

The document concludes that changes in eyelashes and eyelid skin can indicate various local and systemic diseases.

Inflammation affects hair loss; anti-inflammatory treatments may help.

Damaged hair follicles make mice more prone to skin inflammation and skin cancer after UV exposure.

Akt2 protein is essential for normal cell division in early mouse embryos.

A 3-year-old boy lost all his hair due to a rare reaction to phenobarbital, but it grew back after steroid treatment.

Inhibiting class I HDACs helps maintain hair growth ability in skin cells.

Two teenage brothers had a rare, treatment-resistant form of female-pattern hair loss with unusual scalp changes.

Increasing Treg cells in the skin does not cure hair loss from alopecia areata in mice.

A man got a rare rash from the drug topiramate, which went away after he stopped taking it.

The author now believes tricholemmal carcinoma is a rare type of infundibular squamous cell carcinoma and more research is needed on these tumors.

Chitosan-based dressings reduce inflammation and speed up skin wound healing.