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Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Targeting TGFβ can improve skin immunity in older people.

Tph cells are linked to the severity of systemic lupus erythematosus.

JAK inhibitors can effectively reverse hair loss in people with alopecia areata.

New therapies are being developed that target integrin pathways to treat various diseases.

New treatments for COVID-19 show promise, but more effective antiviral drugs are needed.

Certain immune cells contribute to skin autoimmune diseases, and some treatments can reverse hair loss in these conditions.

Loss of OGG1 increases skin inflammation and auto-antibodies in lupus.

Cyclosporin A promotes hair cell growth and affects protein kinase C levels.

RANKL causes lymph nodes to grow by making certain cells multiply.

Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.

PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

Two drugs, ritlecitinib and brepocitinib, improved scalp hair loss condition markers.

Humans and pets share similar allergy mechanisms, and studying pet allergies can help treat both human and animal allergies.

DPCP is effective for treating severe alopecia areata, but relapse is common.

Light therapy can stimulate hair growth and is more effective when started early, but more research is needed on its long-term effects and optimal use.

A protein called lfTSLP is important in causing allergic and other skin diseases and could be a target for treatment.

New treatments like JAK inhibitors show promise for reversing alopecia areata.

The extracellular matrix affects where tumors can start in the body.

IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.

Testosterone's effects on COVID-19 are unclear and need more research.

Healing of heart and skin wounds in animals are similar.

Immune cells in Hidradenitis suppurativa become more inflammatory and may be important for treatment targets.

Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

A gene variant increases the risk of a type of hair loss by affecting hair protein production.

Volatile organic compounds can cause inflammation and increase the risk of autoimmune diseases.

Some drugs may help treat both COVID-19 and radiation injury.

Thymic mesenchymal cells have unique gene expression that supports their specific functions in the thymus.

New treatments like nanotechnology show promise in improving skin cancer therapy.