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Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

Increasing Wnt10b levels can help grow new hair follicles in mice.

Blood stem cells are diverse, influenced by many factors, and understanding them is key for progress in regenerative medicine.

Bone marrow and umbilical cord stem cells can help grow new hair.

Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.

Runx genes are important for stem cell regulation and their roles in aging and disease need more research.

Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

MED1 is essential for normal hair growth and maintaining hair follicle stem cells.

Exosomes from stem cells help hair regrowth by activating a specific signaling pathway.

Fat from the body can help improve hair growth and scars when used in skin treatments.

Using patients' own fat-derived cells to treat alopecia areata significantly improved hair growth and was safe.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Lactilactobacillus curvatus LB-P9 taken orally helps hair regrow faster and thicker in mice.

NIPP1 is important for healthy skin and could help treat skin inflammation.

Alkaline Ceramidase 1 prevents early hair loss in mice by keeping hair follicle stem cells balanced.

Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.

Most people with scarring and nonscarring hair loss show similar D2-40 levels, but some with scarring hair loss have higher levels.

Basonuclin 2 is vital for the development of facial bones, hair follicles, and male germ cells in adult mice, and its absence can lead to dwarfism and abnormal follicles.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

IL-3 worsens lupus nephritis and blocking it improves kidney health.

Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.

The mTOR signaling pathway might play a role in radiation dermatitis, but more research is needed.