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Mice with too much sPLA₂-IIA have hair loss and poor wound healing due to abnormal hair growth and stem cell depletion.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Basonuclin 2 is vital for the development of facial bones, hair follicles, and male germ cells in adult mice, and its absence can lead to dwarfism and abnormal follicles.

The skin's basement membrane is specially designed to support different types of connections between skin layers and hair follicles.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Different markers are found in stem cells of the scalp's hair follicle bulge and the surrounding skin.

Researchers found stem cells in dog hair follicles using specific markers.

Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

CD34 marks potential stem cells in dog hair follicles.

Scientists have made progress in understanding hair follicle stem cells, identifying specific genes and markers, and suggesting their use in treating hair and skin conditions.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

CD99 is highly present in certain skin cells and could help treat skin conditions.

Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.

Fluocinolone acetonide slows down hair follicle stem cells but speeds up skin cell growth in mice.

Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

Ca_v1.2 affects hair growth and could be a target for hair loss treatments.

Vitamin D Receptor is needed for hair growth in mice but not for skin stem cell maintenance.

Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.

Hair follicle regeneration needs special conditions and young cells.

Stem cells can help regenerate hair follicles.

Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

3D microenvironments in microwells improve hair follicle stem cell behavior and hair regeneration.

Hair can regrow after certain stem cells are lost because other stem cells can take over their role.

Hair follicle stem cells in hairpoor mice are disrupted, causing hair loss.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

A protein called EGFR protects hair follicle stem cells, and when it's disrupted, hair follicles can be damaged, but blocking certain pathways can restore hair growth.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.