April 2019 in “Journal of Investigative Dermatology” Testosterone affects androgen receptors and lipid storage in cells, while DHEA does not convert to testosterone or affect these receptors in the same way.
January 2018 in “Elsevier eBooks” The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.
June 2017 in “Journal of The American Academy of Dermatology” LED light helps hair follicle cells grow and prevents them from dying by activating certain cell pathways.
April 2016 in “Journal of Investigative Dermatology” Blocking Oncostatin M's role in the JAK-STAT pathway can stimulate hair growth in mice.
April 2016 in “Journal of Investigative Dermatology” Lithocholic acid helps hair growth and regeneration in alopecia by activating vitamin D receptors.
April 2016 in “Journal of Investigative Dermatology” Blocking Prostaglandin D₂ (PGD₂) could help treat hair loss.
April 2016 in “Journal of Investigative Dermatology” Gypenosides from Gynostemma pentaphyllum were found to have anti-aging effects, increasing skin collagen and reducing wrinkles.
April 2016 in “Journal of Investigative Dermatology” Boosting HGF signaling could improve the creation of hair follicles in lab-made skin.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The back of the scalp has more nerve fibers than the front, which may explain why some people feel more sensitivity there.
April 2016 in “Journal of Investigative Dermatology” Double-stranded RNA activates a pathway that causes a skin protein to be expressed in the wrong place.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” BMP signaling controls hair growth and skin color.
August 2014 in “Plastic Surgery” Dr. WP Unger suggested that traditional strip harvesting might be better for hair transplants than Follicular Unit Extraction due to higher hair survival rates and less risk of a patchy look at the donor site.
May 2014 in “Transfusion and Apheresis Science” PRP is a safe natural treatment that improves skin by reducing wrinkles and enhancing texture for up to 4 months.
May 2014 in “Transfusion and Apheresis Science” PRP treatment showed no hair regrowth improvement after the first application in patients with alopecia.
January 2014 in “Plastic Surgery” Follicular Unit Extraction (FUE) for hair transplants has limitations and may not be suitable for most patients.
January 2014 in “Journal of Investigative Dermatology” Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.
April 2012 in “Annals of Neurosciences” The document concludes that stem cell therapies lack solid proof of effectiveness, except for blood system treatments, and criticizes the ethical issues and commercial exploitation in the field.
July 2009 in “Medical & surgical dermatology” Low-dose acitretin helps nail psoriasis, stem cells may treat scarring alopecia, Chinese men have lower baldness rates, lateral foldplasty is good for ingrown toenails, hair diameter helps diagnose female baldness, childhood trauma linked to alopecia areata, certain hair-weaving leads to scalp conditions in African American women, and new methods for hair research and understanding hair and sweat gland development were introduced.
January 2007 in “The Year book of dermatology” Researchers successfully isolated and identified key stem cells in human hair follicles, which could help develop new skin and hair treatments.
July 1999 in “Journal of The European Academy of Dermatology and Venereology” Bath PUVA therapy works well for a skin condition without as many cancer risks and is cheaper, and iron deficiency might not cause female hair loss.
September 1997 in “Journal of the European Academy of Dermatology and Venereology” Adults can develop late-onset loose anagen syndrome, which may often be misdiagnosed.
September 1997 in “Journal of the European Academy of Dermatology and Venereology” Hirsute women with ovarian-sourced hirsutism are more likely to have irregular periods, with higher BMI and altered hormone ratios.
June 2021 in “Journal of Cosmetic Dermatology” Laser treatment shows promise for hair growth, but needs further research.
June 2020 in “Journal of Investigative Dermatology” Hair growth treatment results vary because each patient's platelets release different levels of growth factors.
April 2019 in “Journal of Investigative Dermatology” Low-level laser therapy helps hair growth and reduces hair loss with few side effects.
January 2015 in “Journal of Cytology and Histology” Hair loss in Androgenetic Alopecia is not caused by damage to follicular stem cells.
September 1997 in “Journal of The European Academy of Dermatology and Venereology” Alopecia linked to higher anxiety and personality disorders.
1533 citations,
October 2008 in “Endocrine reviews” Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
1160 citations,
November 2018 in “Physiological Reviews” The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
1039 citations,
February 2009 in “Nature Reviews Molecular Cell Biology” Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.