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This study demonstrated that CEP may effectively treat pulmonary fibrosis by inhibiting fibroblast activation through regulating macrophage M2 polarization and decreasing fibrosis-associated factors, suggesting a new avenue for future research in this area.

This review examines recent findings on COVID-19 pneumonia treatment using mesenchymal stem cells and reports no new clinical results; the authors highlight MSCs' potential due to their immunomodulatory and tissue-regenerative properties.

This study found that stem cell transplantation effectively reduced acute inflammation-induced testicular damage, suggesting potential for cell-based therapies in addressing male infertility.

This systematic review found that chitosan-based wound therapy may accelerate wound healing by reducing inflammation and modulating immune response, but notes limited clinical trials to date.

In this study, topical piperonylic acid was found to improve wound healing in mice by activating EGFR and modulating gene expression related to the healing process.

This review discusses the role of dermal macrophages in stress-induced hair regeneration and reports no new clinical findings, highlighting the need for further research into macrophage dynamics for potential hair loss therapies.

This review explores the complex role of the Innate Immune System in rheumatoid arthritis, highlighting gaps in understanding its functions and interactions with the Adaptive Immune System, offering insights into potential biomarkers and therapeutic strategies for this challenging autoimmune condition.

This review explores the potential for using exosomes in treating autoimmune skin diseases and promoting skin regeneration, highlighting current applications, delivery methods, and ongoing clinical trials while also identifying challenges and future research directions within dermatology.

This review examines glycopeptide hydrogels as biomimetic materials for tissue regeneration and other biomedical applications, describing their design, properties, and potential uses, and highlighting future advancements in replicating natural tissue environments for precision medicine.

This study suggests that low-dose radiotherapy may lead to temporary neurological improvements in some Alzheimer's patients, with 20% showing cognitive improvement at 6 months; it was well-tolerated, though larger trials are needed for confirmation.

This proof-of-concept study reported that a new, ultra-fast, one-step immunohistochemistry method improved the interpretation of Mohs surgery slides, particularly for poorly differentiated tumors.

This study evaluated the effects of topical glucocorticoids on human skin using non-invasive imaging methods and observed changes such as alterations in skin layer thickness, keratinocyte size, and collagen and elastin signal intensity.

This review highlights that surface mechanical regulation can program macrophage behavior through specific mechanical cues on material surfaces, potentially advancing immunotherapies and regenerative medicine by enabling precise control over macrophage functions.

This study found that dedifferentiated corneal epithelial cells can revert to a stem-cell-like state, aiding tissue homeostasis and repair, with this plasticity limited to the epithelial lineage and enhanced by niche-derived cytokines.

This review summarizes the role of G-protein-coupled receptors in wound healing and reports no new clinical results, highlighting their importance in signaling pathways and recent discoveries in their functions.

This review highlights icariin’s potential to regulate macrophages in varying conditions, discussing its effects on macrophage polarization, metabolism, and disease mechanisms, and noting the development of delivery systems to enhance its therapeutic impact.

This review discusses the potential of metal organic frameworks for drug delivery in wound treatment, highlighting their unique properties and recent research advancements, but reports no new clinical results.

This study found that oral administration of Flammulina velutipes polysaccharide reduced tumor volume and improved survival in mice by modulating macrophage polarization and enhancing antitumor immune responses.

This review integrates studies on mouse models and human clinical observations to highlight the role of immune cells in skin development and how their dysregulation leads to skin disorders, suggesting potential therapeutic pathways for skin regeneration.

In this study, a pH-responsive microneedle patch was developed, showing potential in rat models for treating spinal cord injuries by reducing inflammation, promoting nerve regeneration, and supporting neurogenesis, which contributed to improved motor and neurological recovery.

This research demonstrated that transforming pomelo peel into expanded sponges and carbonized aerogels can accelerate hemostasis and enhance healing in diabetic wounds while eradicating bacterial biofilms, offering an eco-friendly solution for wound care from agricultural waste.

This study synthesizes knowledge of how dendritic cell signals, epithelial integrins, and fibroblast activity converge on TGF-β1 to maintain or disrupt skin healing, contrasting normal and fibrotic scar formation and suggesting possible integrin and immune-targeted treatments for skin fibrosis.

This study found that topical application of TGF-β mimic promoted enhanced wound healing and tissue regeneration in mice, suggesting its potential as a therapeutic option for improving wound healing.

In this study on mice, researchers observed that dermal white adipose tissue (dWAT) plays a key role in regulating skin inflammation and tissue repair; however, reduced expression of certain cytokines in obese mice may hinder these processes, indicating potential metabolic disruptions in dWAT during inflammation.

In this review, the authors highlight the crucial role of mesenchymal stem cells in dermatologic therapies, noting their potential to enhance skin structure and appearance through regenerative mechanisms like inflammation induction, angiogenesis, and recruitment of tissue-specific progenitors.

This review highlights the potential of mesenchymal stem cell secretome for developing topical treatments aimed at skin regeneration and treating various diseases, but notes a lack of studies on safety, efficacy, and standardization processes for its clinical use.

This review introduces the potential of metal-organic framework-based functional composite materials in tissue engineering but reports no new results, emphasizing the need for further innovation in the field.

This study constructed a comprehensive atlas of prenatal human skin, revealing that innate immune cells, such as macrophages, play a crucial role in skin morphogenesis by interacting with non-immune cells, influencing hair follicle formation and angiogenesis beyond their traditional immune functions.

In this study, freezing gamma-irradiated amniotic fluid increased hair follicles and accelerated the transition to the anagen stage in rats, suggesting potential for treating hair loss safely and effectively.

This study found that sulfated CCK octapeptide reduces psoriasis-like skin inflammation in mice, suggesting a new pathophysiological role for CCK in regulating epidermal inflammation.