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This study found that certain C57BL/6 mouse substrains have a genetic vulnerability to skin lesions resembling central centrifugal cicatrical alopecia in humans, potentially worsened by high vitamin A levels.

The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.

Scalp cooling significantly reduces hair loss in chemotherapy patients.

This study reported that inhibiting the JAK-STAT pathway with baricitinib restored cellular homeostasis, delayed senescence, and reduced proinflammatory markers in Hutchinson-Gilford progeria syndrome cell models.

In this study, BLIMP1 was found to function in terminally differentiated epidermal cells to maintain homeostasis, rather than defining a sebocyte progenitor population.

In this study, the Selenium-Chitosan-Mupirocin nanohybrid system significantly enhanced wound healing in a rat model of diabetic wound infection compared to the control, suggesting potential for treating mild diabetic wounds.

This study found that DNA methylation and histone modification status were altered in peripheral blood mononuclear cells of patients with alopecia areata, suggesting these changes may contribute to the disease's pathological immune responses.

This study developed and evaluated a photographic scale to assess CCCA pattern and severity in African American women, finding it reproducible when used by investigators and participants.

This study observed that hair breakage may indicate early central centrifugal cicatricial alopecia in African American women, suggesting that it should be considered in their differential diagnosis.

In this study, transgenic mice with Rank expression in hair follicles showed excessive lymph node growth, which could be normalized by neutralizing the overproduced RANKL, underscoring its role in immune system regulation.

This review article discusses the classification, epidemiology, diagnostic approach, and patient management of lymphocytic primary cicatricial alopecias, without reporting new clinical results.

This study found that selective deletion of Ctip2 in epidermal keratinocytes in adult mice leads to atopic dermatitis-like inflammation and suggests Ctip2 plays a crucial role in skin barrier maintenance and inflammatory regulation.

This study reviewed scalp biopsies from African-American patients, identifying distinct features and diagnostic clues for scarring alopecia types such as traction alopecia and central centrifugal cicatricial alopecia.

This study found that patients with severe vertex pattern androgenetic alopecia had significantly higher carotid intima-media thickness, suggesting an increased risk of subclinical atherosclerosis compared to other alopecia patterns and healthy controls.

This article discusses central centrifugal cicatricial alopecia, highlighting its prevalence, potential genetic factors, and management challenges, but reports no new clinical conclusions and calls for further research.

This study observed that VEGF165 increases proliferation and migration but alters adhesion properties of cultured human hair follicle cells, indicating a potential role for VEGF/VEGFR-2 in hair follicle regulation beyond angiogenesis.

This review discusses the characteristics, impact, and management challenges of central centrifugal cicatricial alopecia and reports no new clinical findings, highlighting the need for further research and early detection strategies.

This article reviews central centrifugal cicatricial alopecia, focusing on its multifactorial etiology and challenges in clinical diagnosis, and calls for more research and better treatment options.

This study suggests that damage to stem cells in the bulge region of hair follicles may contribute to scarring in chronic cutaneous lupus erythematosus.

This study reported that patterns of fibrosis identified through elastin staining may help distinguish specific forms of primary cicatricial alopecia in biopsy specimens, with certain patterns suggesting particular diagnoses.

This study reports that the duration of hair loss is positively associated with the severity of central centrifugal cicatricial alopecia in African-American women.

This study found that horizontal sections of scalp biopsies in patients with Central Centrifugal Cicatricial Alopecia often reveal follicular miniaturization, inflammation, and scarring, which can guide personalized treatment.

This abstract is a listing of affiliations and funding, with no new study or results reported.

This study found that premature desquamation of the inner root sheath is a non-specific histologic feature in scarring alopecia and cannot be used alone to define central centrifugal cicatricial alopecia.

This article discusses central centrifugal cicatricial alopecia, noting its prevalence in women of African descent and highlighting the need for further genetic research to improve treatment options; it reports no new clinical results.

This study found that excessive heat caused the most significant structural changes in hair from Caucasian and Afro samples, especially when combined with other treatments like bleaching and straightening.

This study found that applying topical imiquimod during mid and late telogen in mice activates hair follicle stem cells and influences immune cell infiltration, promoting hair cycle entry independently of Wnt signaling.

This study found that central centrifugal cicatricial alopecia primarily affects adult women of African descent and suggests an association with traumatic hair care practices and delayed diagnosis.

This study identified upregulation of genes linked to fibroproliferative disorders, such as platelet-derived growth factor and collagen genes, in patients with central centrifugal cicatricial alopecia, suggesting potential therapeutic targets.

This study found that hair transplantation using round grafts improved hair growth in African American women with end-stage CCCA, showing no postoperative scarring in the donor or recipient areas.