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PCOS symptoms change with age; younger women have higher androgen levels and less metabolic issues, while older women face more metabolic challenges despite milder PCOS symptoms.

Using dermoscopy to guide scalp biopsies is an effective way to diagnose cicatricial alopecia.

Light can turn on hair growth cells through a nerve path starting in the eyes.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.

Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.

Small white dots on the scalp seen with a dermoscope correspond to sweat ducts and vary with different hair disorders.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.

Apoptosis is crucial for healthy skin and treating skin diseases.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

Finasteride may help treat chronic CSC, improving vision.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Testosterone may slow down wound healing and increase inflammation.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

Female pattern hair loss is common, linked to polycystic ovarian syndrome, and treated with topical Minoxidil.

Improving the environment and cell interactions is key for creating human hair in the lab.

Vitamin D receptor is crucial for starting hair growth after birth.

Acne severity is linked to higher levels of certain androgenic hormones, even when those levels are within the normal range.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

Ablative fractional resurfacing could improve how well topical drugs penetrate the skin, but more research is needed to fine-tune the method.

Tofacitinib is somewhat effective for alopecia areata, but more research is needed on its safety and long-term effects.

miR-218-5p helps skin and hair growth by targeting SFRP2 and activating a specific signaling pathway.

Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.

HIV can cause various severe or unusual skin conditions that help indicate the presence and stage of the disease.

Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.

The document concludes that hair transplantation and gene therapy may be important for future hair loss treatment.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.