August 2024 in “Majalah Obat Tradisional” This study found that microemulsions containing ethanol extract of cayenne pepper were effective in enhancing hair growth in rabbits, with the 0.2% concentration achieving the most significant results over a 30-day period, compared to a negative control.
January 2024 in “Estetologia Medyczna i Kosmetologia” In this study analyzing trichological shampoos on the Polish market, researchers reported that most active ingredients claimed to combat hair loss were found in only one product each, questioning the scientific evidence supporting these claims.
June 2021 in “Journal of Pharmaceutical Care Anwar Medika” This study investigated the physical stability of hair tonic formulations made from ethanol extract of cayenne pepper leaves, finding that formulations with specific concentrations of propylene glycol and ethanol had good physical stability.
191 citations
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February 2002 in “Archives of Dermatology” This review discusses herbal therapies for dermatologic disorders, focusing on those with scientific evidence of efficacy and common interactions, but reports no new clinical results.
9 citations
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March 2011 in “Oxidative stress and disease” This review explores herbal medications for skin disorders, covering their clinical efficacy, safety, and common drug interactions, but reports no new clinical results.
2 citations
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September 2025 in “Food Production Processing and Nutrition” This review highlights capsaicin's chemical properties, natural sources, and its potential benefits such as antioxidant, anti-inflammatory, and analgesic effects, while also noting its challenges in food applications regarding dosage, taste perception, and regulatory compliance.
74 citations
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August 2006 in “Journal of clinical gastroenterology” This report describes a case of acute liver injury in a woman following the use of Shen-Min, a herbal hair growth supplement, highlighting a potential link to acute hepatitis.
January 2020 in “Asian journal of applied science and technology” This source provides an overview of the dietary recommendations for macronutrient intake and the benefits of plant-based diets, including meeting essential amino acid needs through combining plant proteins and the advantages of consuming complex carbohydrates and adequate fiber for health.
October 1890 in “Science” Pilocarpin can cause hair regrowth and color change in some cases but not in others, and it may have side effects in animals.
January 2017 in “Springer eBooks” The document explains various skin conditions and their treatments.
Use the least toxic, most specific treatments for skin diseases, considering side effects and individual patient needs.
9 citations
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December 2022 in “Phytomedicine” This review discusses the pharmacology, toxicology, and clinical efficacy of flavonoids and saponins, highlighting the need for more data on their pharmacokinetics, interactions, and toxicities as most research is still in vitro.
11 citations
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September 2021 in “Anais Brasileiros de Dermatologia” This article reviews how skin manifestations can aid in diagnosing various systemic diseases, focusing primarily on their association with rheumatologic conditions while also addressing vascular, granulomatous, and other disease impacts, aiming to provide dermatologists with practical diagnostic insights.
6 citations
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May 2024 in “Frontiers in Pharmacology” This review discusses the potential of natural products to induce ferroptosis as a promising therapeutic strategy for non-small cell lung cancer and reports no clinical results; the authors highlight the need for further comprehensive studies.
3 citations
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February 2020 in “International journal of women’s dermatology” Most women with hair loss take more supplements than average, but these often don't help and can be risky and costly.
February 2024 in “Mikailalsys Journal of Mathematics and Statistics” This study suggests that the non-seasonal Holt-Winters method effectively forecasts stock price returns for companies affected by the BDS action, with five out of six stocks showing decreases.
December 2024 in “Journal of Population Therapeutics and Clinical Pharmacology” According to this worldwide systematic review, psoriasis is a prevalent disease with adult prevalence ranging from 0.53% to 11.48%, more common in older populations and with substantial knowledge gaps in low and middle-income countries.
December 2020 in “Jurnal Kedokteran Hewan” In this study, researchers found that cayenne leaf extract significantly enhanced hair length and quantity in mice, with a 10% concentration being the most effective for stimulating growth.
October 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This source describes Protetox as a natural dietary supplement that aids in weight loss by detoxifying the body, utilizing a blend of plant-based ingredients and antioxidants, and claims users have reported significant weight loss without changing their diet or exercise routines.
2 citations
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September 2011 in “Revista de Ciências Farmacêuticas Básica e Aplicada” This study examined a shampoo containing chili pepper extract and biopolymer microspheres for hair loss treatment, finding that it was well tolerated by volunteers, particularly due to the exfoliation sensation.
February 2026 in “International Journal of Molecular Sciences” This study investigated the photoprotective properties of Brazilian pepper tree extract against UV-induced damage in skin cells, reporting that it enhanced expression of genes relevant to skin health and showed superior activity compared to standard antioxidants.
This study found that papaya seed extract gel accelerated hair length growth in rabbits, with the most effective concentration being 15%, though it did not significantly affect hair mass.
April 2022 in “Journal of applied science and environmental management” This study found that Aframomum melegueta seed extract improved wound healing in albino rats, with treated groups showing smaller wound sizes and formation of new tissues compared to controls.
September 2022 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, Amazonian pepper extracts showed potential as an ingredient for alopecia treatment due to their promising chemical profile, low cytotoxicity, and compatibility with shampoo formulations.
May 2025 in “Indian Journal of Pharmacology” In this study, researchers reported that standardized rosemary and capsicum extracts significantly improved hair growth parameters such as follicle density, length, and diameter in rats with testosterone-induced alopecia, suggesting these extracts may aid in more effective natural treatments for androgenetic alopecia.
June 2022 in “Journal of Holistic and Health Sciences (Jurnal Ilmu Holistik dan Kesehatan)” This study found that a powder made from papaya seeds and celery leaves remained stable for 3 weeks when stored at room or cold temperatures, suggesting potential for hair health applications.
18 citations
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February 2024 in “Nutrients” This study investigated a novel extract from pomegranate byproducts, finding it effective in reducing blood pressure and inflammation in hypertensive rats, comparable to Captopril, while also highlighting the extract's potential to enhance the pomegranate supply chain and environmental benefits.
4 citations
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October 2021 in “International Journal of Cosmetic Science” This study found that C. japonicum flower extract significantly increased melanin content and cellular activity in human melanocytes and may improve follicular depigmentation and vitiligo through cAMP signaling.
5 citations
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January 2018 in “Skin Pharmacology and Physiology” This study found that a high sesquiterpene C. aeruginosa extract significantly reduced axillary hair growth in women compared to placebo with no apparent adverse effects.
3 citations
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July 2013 in “Bioscience, Biotechnology, and Biochemistry” This study found that topically applied Chinese black tea extract, when fermented and combined with capsaicin, significantly promoted hair growth in mice, potentially involving estrogen receptor interactions.