1 citations
,
January 2019 in “Archives of Clinical and Medical Case Reports” In this study, researchers identified two mechanisms of lipid loss from hair when exposed to surfactants, with the mechanism depending on the lipid's hydrophobicity.
1 citations
,
July 2025 in “Chemosensors” This study developed a closed-loop system for emergency wound care that monitors infection in real-time using biomarkers and delivers amikacin-loaded liposomes for treatment, integrating a conductive hydrogel for environmental protection and antibacterial benefits.
November 2025 in “Advanced Healthcare Materials” This study found that incorporating CTA2-BADG, a modified hair-rebonding compound, into damaged hair significantly improved surface morphology and tensile strength by using charge-conversion chemistry to enhance penetration into the hair shaft.
November 2025 in “Cosmetics” This study evaluated a levan-based polysaccharide, POLEVAN®, in shampoo formulations and reported that it significantly increased hair glossiness by 24%, allowed a reduction of surfactant content by up to 50% without affecting foam, and maintained scalp moisturization similar to hyaluronic acid in a clinical setting.
December 2023 in “Journal of molecular structure” This study found that hair membrane fluidity is low in the cuticle but high in the cortex and medulla, with treatments like ionic surfactants and oleic acid increasing fluidity in hydrated hair; however, dehydration significantly reduces fluidity throughout the hair.
2 citations
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May 2025 in “Skin Appendage Disorders” This review highlights the benefits and controversies of silicones in hair care, emphasizing their ability to improve hair texture and moisture retention while addressing environmental concerns and product buildup.
3 citations
,
January 2022 in “Pharmaceutics” This review examines new formulations for delivering 5-α-reductase inhibitors to improve targeted drug delivery in androgenetic alopecia, but reports no new clinical results.
2 citations
,
January 2009 in “Journal of Drug Delivery Science and Technology” This study found that cationic vesicles enhanced minoxidil skin retention and in vivo hair growth efficacy compared to other formulation types due to electrostatic interactions with the skin.
11 citations
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June 2025 in “Polymers” This review reports on recent surfactant-based niosome formulations, including those with polysaccharides, for versatile drug delivery applications such as ocular, oral, and transdermal settings, while discussing their limitations and potential prospects.
November 2023 in “ACS Omega” This study reported that a novel cationic liposome formulation for delivering encapsulated Cas9 protein and sgRNA successfully decreased SRD5α2 mRNA expression by 29.7% in vitro, suggesting a potential alternative treatment option for conditions like prostate cancer and benign prostatic hyperplasia without current drug side effects.
September 2025 in “Advanced Pharmaceutical Bulletin” This review highlights the promise of non-viral gene delivery systems, particularly genosomes, over traditional viral vectors due to enhanced safety and efficiency in therapeutic nucleic acid delivery for genetic diseases like cystic fibrosis and malignancies.
59 citations
,
October 2012 in “Pharmaceutical Research” This study found that nanostructured lipid carriers with more soybean phosphatidylcholine provided better skin retention and follicular targeting for diphencyprone compared to other formulations and controls.
14 citations
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November 2024 in “Pharmaceuticals” This study found that using spanlastics, a nano, surfactant-based drug delivery system, improved the bioavailability, drug release characteristics, and pharmacokinetic behavior of famotidine, a poorly soluble drug, by enhancing its dissolution and membrane permeation.
30 citations
,
December 2019 in “PLoS ONE” This study found that formulating raloxifene in nano-lipid carriers significantly enhanced its permeation and cytotoxicity against cancer cells compared to raw raloxifene.
1 citations
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September 2025 in “Scientific Reports” This study reported that a colistin sulfate-loaded nanoemulgel showed improved antimicrobial activity and skin permeability compared to a CS solution, suggesting a potential new approach for treating severe infections caused by multidrug-resistant bacteria.
January 2013 in “Springer eBooks” Hair care products are important for appearance and self-esteem, and choosing the right ones can help maintain healthy hair.
47 citations
,
May 2021 in “Polymers” This review surveys the chemical composition and various uses of jojoba oil in medicine and industry but presents no new clinical results.
9 citations
,
November 2009 in “Recent Patents on Drug Delivery & Formulation” This review discusses various patent articles on microemulsion carriers in drug delivery systems and reports no new empirical findings.
2 citations
,
May 2023 in “Nanomaterials” This review explores the formulation, characterization, and applications of microemulsions, highlighting their potential for enhanced cutaneous drug delivery by improving bioavailability and enabling sustained release of both hydrophilic and hydrophobic drugs.
14 citations
,
February 2025 in “Pharmaceutics” This review highlights recent advancements in using niosomes as nanocarriers for improved delivery and sustained release of active cosmetic compounds, discussing their properties, applications, and future potential in cosmetic chemistry.
1 citations
,
May 2022 in “Pharmaceutics” This study found that a developed nanostructured lipid carrier formulation of tea seed oil can effectively stimulate hair growth and reduce the oily feeling associated with direct application.
92 citations
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April 2021 in “Pharmaceutics” This review discusses the applications and challenges of lipid nanosystems in various fields, comparing techniques for evaluating nanoparticle properties, and reports no new experimental results.
March 2011 in “Focus on surfactants” Several companies launched new hair care ingredients in 2011 to improve conditioning, color retention, combability, and heat protection.
4 citations
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March 2021 in “Journal of Surfactants and Detergents” This study found that hair treated with shampoo containing water-soluble silicone demonstrated smoother sliding and better detangling, compared to shampoo with water-insoluble silicone, due to differences in conditioning film formation.
8 citations
,
July 2012 in “Annals of biomedical engineering” This study found that the uptake of molecules by hair is influenced by both hydrophobic and ionic charge interactions, with binding affinity decreasing as pH approaches the solute's dissociation constant.
4 citations
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November 2017 in “Journal of Cosmetic Dermatology” This study found that polyquaternium-68 at pH 9 achieved the greatest hair deposition, while polyquaternium-44 demonstrated the best wash resistance at pH 6.
This chapter provides an overview of the complex chemical and physical structure of the hair surface, detailing how factors like ethnicity, environmental stress, and cosmetic treatments can alter its properties and influence the adhesion of hair care products.
December 2023 in “International Journal of Newgen Research in Pharmacy & Healthcare” This study evaluated the physicochemical characteristics, safety, and efficacy of six herbal and six synthetic shampoos and found that all products performed well in various tests, with no skin irritancy observed, suggesting that both types can be considered safe for use.
September 2025 in “Cureus” In this case report, the researchers documented a rare instance of plica neuropathica, characterized by matted and twisted hair, occurring alongside diffuse alopecia, marking the first such documented association and emphasizing its diagnostic challenges in identifying causes of alopecia.
January 2021 in “Nasza Dermatologia Online” This case report describes a 50-year-old Kashmiri woman with plica polonica, detailing trichoscopic findings of entangled hair with crisscrossing shafts and concretions.