January 2011 in “Journal of Society of Cosmetic Chemists of Japan” This study found that a conditioner containing 18-MEA and SPDA can improve hair's smoothness and reduce flyaways, enhancing hair manageability.
8 citations
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May 2020 in “International journal of biological macromolecules” In this study, researchers evaluated the binding of keratin-associated proteins and α-keratins to human hair fibers, finding that chemical preactivation significantly enhanced binding to natural hair, while perming altered binding characteristics and increased penetration depth.
This study found that high-charge-density cassia HPTC improves deposition efficiency and conditioning benefits in shampoos compared to quaternized guar, suggesting its potential as an alternative or adjunct conditioning agent.
1 citations
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September 2008 in “International Journal of Cosmetic Science” This study found that high-charge-density cassia HPTC improves deposition efficiency and conditioning benefits in shampoos compared to quaternized guar, suggesting its potential as an alternative or adjunct conditioning agent.
November 2025 in “Advanced Healthcare Materials” This study found that incorporating CTA2-BADG, a modified hair-rebonding compound, into damaged hair significantly improved surface morphology and tensile strength by using charge-conversion chemistry to enhance penetration into the hair shaft.
97 citations
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January 2005 in “Wear” In this study, the researchers measured and discussed the friction and wear properties of various hair types against synthetic skin and other hair, finding variations based on factors like ethnicity, hair condition, and environmental conditions.
25 citations
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May 2019 in “Cosmetics” This paper reviews the surface degradation of hair and describes how combining 18-MEA with specific surfactants can maintain hydrophobicity on bleached and weathered hair surfaces.
2 citations
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July 2023 in “Cosmetics” In this study, researchers highlighted that while hair lipids are crucial for hair health and protection, surfactants in shampoos and conditioners can partially remove these lipids, potentially affecting hair structure, though the exact mechanisms remain poorly understood and require further investigation.
January 2023 in “Fashion and textiles” This study found that hair dyed with anionic basic hair dye lost more color after shampooing compared to cationic and nonionic dyes, with alkaline shampoo increasing this effect.
2 citations
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September 2025 in “Antioxidants” This review highlights that nano-antioxidants show promise as a treatment strategy for immune-mediated inflammatory diseases, like autoimmune and chronic inflammatory conditions, due to their improved stability and targeted delivery, but notes that further research is necessary to optimize their use and assess long-term safety.
161 citations
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April 2006 in “Journal of Investigative Dermatology” Liposomes with certain properties can effectively deliver drugs deep into hair follicles.
84 citations
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April 2015 in “Cosmetics” This review discusses various types of hair dyes, their mechanisms of action, molecular structures, application methods, and formulation aspects, but reports no new research findings.
42 citations
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November 2022 in “Cosmetics” This review concluded that using niosomes in cosmetics significantly enhances the aesthetic and therapeutic effects of skin and hair products, potentially aiding in treating skin conditions.
16 citations
,
June 2025 in “Journal of Composites Science” This study investigated chitosan–hydroxyapatite biocomposites, finding them to enhance anti-inflammatory cytokine expression, support cellular activities, and reduce pro-inflammatory cytokines in a dermatitis model, while highlighting gaps in understanding their immune modulation and issues with reproducibility for clinical use.
13 citations
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November 2022 in “Future Journal of Pharmaceutical Sciences” This review examines liposome-based cosmeceuticals for various skin conditions and reports no new clinical results, highlighting the potential promise these formulations offer for future applications.
4 citations
,
March 2013 in “InTech eBooks” Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.
2 citations
,
September 2025 in “International Journal of Nanomedicine” This review discusses the roles of extracellular vesicles in skin health and disease and reports no clinical results; the authors highlight potential therapeutic uses and call for more research.
1 citations
,
July 2025 in “Chemosensors” This study developed a closed-loop system for emergency wound care that monitors infection in real-time using biomarkers and delivers amikacin-loaded liposomes for treatment, integrating a conductive hydrogel for environmental protection and antibacterial benefits.
August 2023 in “Clinical, Cosmetic and Investigational Dermatology” This study identified key trends and influential contributors in skin microbiome research from the past decade, highlighting the growing publication rates, major players like the USA, and prominent researchers such as Gallo RL.
99 citations
,
July 2005 in “Ultramicroscopy” This study analyzed the nanotribological properties of various hair types and human skin, revealing differences in friction and adhesion based on ethnicity and hair condition.
81 citations
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December 2007 in “Acta materialia” This study conducted in situ tensile loading experiments with atomic force microscopy to observe how conditioning treatments affect the tensile response of virgin, chemically damaged, and mechanically damaged Caucasian hair.
51 citations
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March 2001 in “Clinics in dermatology” This study found that bleach treatments significantly increased hair surface roughness and decreased Young's modulus, indicating marked changes in hair's molecular structure which may affect future hair-care product formulation.
1 citations
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July 2019 in “Microscopy Today” This source highlights the utility of cationic polymers in haircare products for protecting against hair damage from chemical treatments and grooming, and describes how microfluorometry can measure polymer deposition and penetration on hair fibers.
December 2025 in “Cosmetics” In a laboratory study, researchers found that a novel Bioactive Crosslink Repair Complex improved both the protection and repair of chemically damaged hair, enhancing tensile strength, shine, and cuticle alignment when added to bleaching mixtures and leave-in conditioners.
50 citations
,
April 2021 in “Frontiers in Immunology” This review discusses neuroimmune communication in skin disorders and peripheral neuropathic pain, highlighting the complex interactions between sensory neurons and immune cells; it reports no new clinical results but suggests potential future therapies.
7 citations
,
August 2022 in “Journal of Nanobiotechnology” This review discusses recent advances in stimuli-responsive nanoformulations for CRISPR-Cas9 delivery, highlighting their design rationales and potential biomedical applications, but reports no new experimental results.
8 citations
,
January 2012 in “International journal of polymer analysis and characterization/IJPAC. International journal of polymer analysis and characterization/IJPAC. International journal of analysis and characterization” This study found that hydrogenated palm oil effectively conditions damaged hair by preventing water-induced swelling, with TOF-SIMS analysis showing that its component tripalmitin penetrates the hair's cuticle and outer cortex.
December 2025 in “VNU Journal of Science Medical and Pharmaceutical Sciences” This review synthesizes evidence supporting the efficacy of PRP in dermatological conditions like wound healing and alopecia, but emphasizes the need for standardized protocols and larger randomized controlled trials.
34 citations
,
September 1992 in “Journal of the American Academy of Dermatology” This article provides dermatology residents with essential information on cosmetic use to help manage skin conditions and reactions, without reporting new clinical results.
September 2025 in “Drug Design Development and Therapy” This study suggests that while platelet-rich products show promise in treating dermatological conditions like chronic wounds and skin aging, there is still a need for standardized methodologies and extensive trials to confirm their long-term clinical benefits.