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This study found that Flammulina velutipes polysaccharides-derived scaffolds greatly enhanced wound healing and hair follicle regeneration in a rat model, particularly with the FPS/NaOH variant showing the best results.

This study found that male 5α-reductase 2 knockout mice showed deficits in social dominance behaviors and reduced dopamine receptor binding in a brain region related to social ranking.

This study identified significant changes in the expression of nine proteins in the nucleus accumbens of rats treated with finasteride, suggesting potential novel targets for its neuropsychiatric effects.

This study found that phyto-vesicles of ß-sitosterol showed better absorption and improved activity for treating androgenetic alopecia in rats compared to the compound and its complex.

This study found that a synthetic avicequinone C analogue, 5e, was significantly more potent in inhibiting steroid 5α-reductase type 1 activity in human keratinocytes compared to the original isolated compound.

This study found that the PP2A-B55α regulatory subunit is crucial for ectodermal development in mice, with knockout embryos displaying severe neural and epidermal defects and failing to survive to birth.

In this study, 4-substituted N-(1,1-dimethylethyl)-3-oxo-4-androstene-17.beta.-carboxamides were synthesized and evaluated in vitro as potential 5 alpha-reductase inhibitors and antiandrogens.

This review discusses differences in ERβ signaling between rodents and humans and reports no new clinical results; the authors highlight the need for further research in humans before using ERβ agonists clinically.

This study found that 15-dPGJ2 promotes apoptosis in human follicular keratinocytes, suggesting its potential role in developing hair loss prevention treatments through DP2 antagonism.

This paper reviews the role of the telomere-telomerase system in cellular ageing and cancer, discussing potential therapies but reporting no new experimental results.

This review discusses the design and advances of lipid–polymer hybrid nanoparticles as promising delivery systems for genome editing strategies, highlighting their potential in biomedical applications.

This study identified two cytochrome P450 enzymes in Avicennia marina leaves that may contribute to the biosynthesis of triterpenoids, potentially responsible for the plant's medicinal properties.

In this study, treatment with finasteride altered the expression patterns of antioxidant enzymes in the epididymis of rats, potentially affecting its protective function for spermatozoa.

This review discusses the importance of heme oxygenase in skin physiology and disease, but it reports no new clinical results; the authors highlight its potential as a treatment target for conditions like atopic dermatitis and psoriasis.

This study found that carbonic anhydrase II was significantly upregulated in human keratinocytes when treated with toll-like receptor 3 agonist and Th2 cytokines, suggesting its potential role in inflammatory skin conditions.

This study found that COX-2 expression in normal rat skin is linked to the hair cycle, with varying levels observed in different skin structures during anagen, catagen, and telogen phases.

This article reviews treatment options for male androgenetic alopecia, including their distinct aims of arresting progression, stimulating regrowth, and concealing hair loss, and reports no new clinical results.

Finasteride doesn't affect antipyrine metabolism, so interactions with cytochrome P-450 enzyme drugs are unlikely.

This review discusses the role of Cytochrome P-450 in dermatology and reports no new clinical results.

In this study, Akt2 and the oncogenic protein Tcl1 were found to be essential for early blastomere proliferation and embryo development in preimplantation mouse embryos.

In this study, anti-androgenic therapy with finasteride for prostate disease was associated with reduced cardiac hypertrophy in heart failure patients, encouraging further investigation in larger cohorts.

This study found that ethanolic and petroleum ether extracts of Cuscuta reflexa, as well as an isolate from these extracts, improved hair growth and follicle characteristics in androgen-induced alopecia in rats.

This study found that inhibiting class I histone deacetylases in postnatal mouse dermal cells preserved their ability to induce hair follicles during culture by increasing specific gene expressions and activating the Wnt signaling pathway.

This study reported that newly synthesized nonsteroidal compounds were effective at inhibiting prostatic 5 alpha reductase isozyme 2, especially the compound with an N, N-diisopropylcarbamoyl substituent, suggesting potential for treating benign prostatic hyperplasia.

MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.

In this study, Trf1 genetic deletion in mice, including those with cancer-prone mutations, was shown to not affect overall viability and cause only mild effects, while being necessary for tumor formation, suggesting a potential therapeutic window for Trf1 as an anti-cancer target.

This study found that all-trans retinoic acid (ATRA) negatively affects hair growth by reducing goat dermal papilla cell viability and growth factor expression.

Researchers made two new compounds that could be used for medicine.

This study reports that military hair-grooming standards have evolved to support inclusivity by addressing racial diversity in hair and skin types, aiming to eliminate the adverse effects of tight hairstyles and reduce racial and gender bias.

This study found that patients experiencing hair loss had significantly lower serum levels of zinc and copper compared to healthy controls.