31 citations
,
August 2005 in “The American Journal of Dermatopathology” This study investigated the histopathology of ectodermal dysplasia/skin fragility syndrome, identifying specific skin and hair abnormalities associated with PKP1 gene mutations in two young female patients.
29 citations
,
September 2012 in “Dermatologic Clinics” This article reviews the causal mechanisms of hair follicle disorders, focusing on inflammation, genetics, environment, and hormones, but it reports no new clinical results.
19 citations
,
April 2015 in “International Journal of Molecular Sciences” This study identified distinct gene expression patterns in wool follicle bulbs that may play important roles in wool follicle cycling and regeneration in sheep.
10 citations
,
January 2014 in “Genetics and Molecular Research” This study observed that primary hair follicles in Liaoning Cashmere goats had broader hair bulb widths compared to secondary follicles, with the difference diminishing during the anagen phase of hair follicle development.
10 citations
,
January 2009 in “Elsevier eBooks” This review discusses the structure, functions, and growth cycle of human hair, emphasizing its reduced growth and protective roles, and reports no new research findings.
6 citations
,
January 2009 in “Elsevier eBooks” This chapter discusses the structure and function of the skin, detailing its protective roles and the layers that comprise it, but reports no new research findings.
3 citations
,
June 2006 in “Expert Review of Dermatology” This review discusses recent advances in hair follicle research, highlighting therapeutic and cosmetic applications, but reports no new study results.
2 citations
,
December 2023 in “Royal Society of Chemistry eBooks” The book discussed in this abstract is a comprehensive guide to hair analysis, detailing the latest methods and applications across various fields such as toxicology and drug monitoring, designed for both newcomers and experts in the field.
2 citations
,
February 2014 in “Animal Biotechnology” This study reported that the PTGER2 gene is strongly expressed in cashmere goat skin and its expression tends to decrease from the anagen to telogen stages of the hair follicle cycle.
January 2015 in “Springer eBooks” Hair health is influenced by genetics, aging, and environmental factors, with proper care needed to maintain it.
February 2010 in “Journal of The American Academy of Dermatology” Mimicking growth factors in a topical solution can prolong hair growth phase and reduce hair loss without side effects.
60 citations
,
October 2005 in “Experimental Dermatology” This study found that high-dose oral zinc significantly influences hair growth in mice, showing both inhibition and promotion effects depending on the timing and duration of administration.
26 citations
,
October 2007 in “Experimental Dermatology” This study found that l-carnitine stimulated hair growth in vitro by promoting proliferation and reducing apoptosis in human scalp hair follicles, suggesting potential as a treatment for hair loss.
6 citations
,
November 2010 in “Histochemistry and cell biology” This study found that transthyretin and megalin expression in human scalp hair follicles varies significantly with the hair growth cycle, peaking during anagen and diminishing in catagen and telogen phases.
15 citations
,
February 2015 in “Cell & tissue research/Cell and tissue research” This review examines the role of P-cadherin in skin and hair biology, emphasizing its importance in human hair growth, cycling, and pigmentation, and reports no new research findings.
94 citations
,
July 2003 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that continuous expression of epidermal growth factor in transgenic mice prevented hair follicles from entering the catagen phase, implicating EGF as a crucial regulator in hair cycle progression.
86 citations
,
August 2000 in “Pigment cell research” This study observed that melanogenesis in human hair follicles is linked to anagen phases, with melanocyte activity and enzyme expression being region-specific to the nascent bulb.
4 citations
,
January 2014 in “PubMed” This review discusses the cyclical phases of hair follicle transformation and the various factors that regulate hair growth, reporting no new clinical results.
45 citations
,
January 2010 in “Forensic science international” This review discusses fetal hair follicle development and its importance for determining in utero drug exposure through neonatal hair, but it reports no new clinical results.
22 citations
,
June 2008 in “Experimental Dermatology” This study found that heparanase is primarily located in the inner root sheath of human hair follicles during the anagen phase, and inhibiting it in cultured hair follicles induces a catagen-like process.
19 citations
,
January 2019 in “Animals” This study suggests that PDGFA and BMP2 play a role in the hair follicle cycle in cashmere goats, with PDGFA particularly involved in activating the growth phase.
50 citations
,
March 2018 in “BMC Genomics” This study expands knowledge of non-coding RNAs in goats and other mammals, enhancing understanding of their roles in hair follicle growth and regression.
27 citations
,
September 2015 in “Drug Design Development and Therapy” This study suggests that type IV collagenases, MMP-2 and MMP-9, play important roles in the hair cycle by regulating the expression of VEGF, IGF-1, and TGF-β in mice.
14 citations
,
May 2017 in “InTech eBooks” This chapter reviews the anatomy and physiology of hair follicles but reports no new research findings or clinical results.
11 citations
,
May 2012 in “Genesis” This study in mutant mice found that Bmpr2 and Acvr2a are individually redundant, but together essential for normal hair follicle development, with their reduction causing rapid hair cycling and graying.
67 citations
,
July 2000 in “Proceedings of the National Academy of Sciences” This study developed a follicular automaton model that simulates human hair cycle dynamics and can replicate hair pattern changes associated with diffuse or androgenetic alopecia.
July 2024 in “Skin Research and Technology” This study found that combining Bioscalp with Ultra Exo Booster and Ultra S Line Plus significantly promoted hair growth and maintained hair bulb integrity in cultured hair follicles from Korean adults.
99 citations
,
September 2007 in “The American journal of pathology” This study found that organ-cultured human scalp hair follicles can mimic chemotherapy-induced damage in vivo and serve as a model to explore molecular targets and protective agents for hair follicle preservation.
72 citations
,
January 2012 in “Annals of Dermatology” In this study, IGF-I was shown to enhance human hair follicle growth, maintain the anagen phase, and increase expression of certain growth factors and anti-apoptotic markers.
40 citations
,
May 2005 in “Journal of Cell Science” In this study, transgenic mice expressing a truncated form of latent transforming growth factor-β-binding protein exhibited altered hair cycles due to increased active transforming growth factor-β, impacting keratinocyte proliferation and hair cycle phases.