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Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.

Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Platelet-rich plasma can potentially promote hair growth by stimulating cell growth and increasing certain proteins.

Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

Apoptosis is essential for human skin development and forming a functional epidermis.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

PGD2 stops hair growth and is higher in bald men with AGA.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Blocking JAK-STAT signaling can lead to hair growth.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Cathepsin L is essential for normal hair growth and development.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

EGFR inhibitors often cause skin problems and other side effects, but these are usually reversible and can be managed to keep patients comfortable.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.