65 citations,
November 2016 in “Journal of The American Academy of Dermatology” The document concludes that early recognition and treatment of primary cicatricial alopecia is crucial to prevent permanent hair loss.
49 citations,
October 2017 in “Nutrients” Equisetum debile extract, especially the ethyl acetate type, may be a promising natural ingredient for anti-hair loss products.
28 citations,
July 2008 in “Developmental Biology” Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.
72 citations,
April 2008 in “Organogenesis” Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.
6 citations,
August 2007 in “Journal of Surgical Research” Mice genetically modified to produce more Del1 protein had faster hair regrowth.
142 citations,
March 2019 in “Molecules/Molecules online/Molecules annual” Cannabinoids may help treat various skin conditions.
46 citations,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Disrupting Acvr1b in mice causes severe hair loss and thicker skin.
12 citations,
May 2015 in “Molecular Medicine Reports” Troxerutin helps protect skin cells from oxidative stress and may be good for treating hair loss.
16 citations,
September 2018 in “Journal of Ethnopharmacology” Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.
Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.
September 2017 in “Asian Journal of Beauty and Cosmetology” The Notch signaling pathway is important for hair follicle development and could help create treatments for hair disorders.
82 citations,
February 2017 in “Cold Spring Harbor Perspectives in Biology” The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
7 citations,
December 2016 in “Journal of The Taiwan Institute of Chemical Engineers” Pig blood plasma can be used to promote human hair growth and is a good alternative to the commonly used serum additive.
12 citations,
August 2013 in “Journal of Dermatological Science” The MAGE3 hypothesis for alopecia areata did not lead to a significant breakthrough.
16 citations,
December 2006 in “Expert Review of Dermatology” Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.
32 citations,
December 2017 in “International Journal of Molecular Sciences” Low vitamin D might be linked to certain types of hair loss, and supplements could help, but more research is needed.
23 citations,
April 2021 in “Journal of Clinical Medicine” Frontal Fibrosing Alopecia's cause is unclear, affects mainly postmenopausal women, and current treatments focus on stopping hair loss rather than regrowth.
June 2024 in “Regenerative Therapy” Exosomes from stem cells may help rejuvenate skin and regrow hair, but more research is needed.
9 citations,
February 2021 in “Frontiers in Cell and Developmental Biology” Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.
Combining PRP with a special lotion is more effective for hair loss than PRP alone.
27 citations,
September 2018 in “Nanomedicine: Nanotechnology, Biology and Medicine” Further research is needed to improve hair regeneration using stem cells and nanomaterials.
14 citations,
October 2020 in “Scientific reports” Hair greying is linked to reduced ATM protein in hair cells, which protects against stress and damage.
3 citations,
August 2020 in “International Journal of Molecular Sciences” Blocking Rab27a slows hair growth, while blocking Rab27b encourages it.
Researchers found a genetic link for hereditary hair loss but need more analysis to identify the exact gene.
3 citations,
October 2023 in “Military Medical Research/Military medical research” Regulatory T cells help heal skin and grow hair, and their absence can lead to healing issues and hair loss.
16 citations,
October 2018 in “Biochemical and Biophysical Research Communications” Sildenafil, often used for erectile dysfunction, may help hair growth.
1533 citations,
October 2008 in “Endocrine reviews” Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
26 citations,
February 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” An enzyme other than TNAP might be responsible for vitamin B-6 metabolism in the skin.
January 2012 in “Elsevier eBooks” Hair loss can cause emotional and social issues, and various treatments, including medication, surgery, and psychological support, are needed.
30 citations,
December 2017 in “Medical Hypotheses” The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.