research Increasing GSH-Px Activity and Activating Wnt Pathway Promote Fine Wool Growth in FGF5-Edited Sheep
Editing the FGF5 gene in sheep increases fine wool growth.
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690-720 / 1000+ resultsresearch Age-Associated Decrease in GDNF and Its Cognate Receptor GFRα-1 Protein Expression in Human Skin
Human skin has less GDNF and its receptor with age.
research Hairless Suppresses Vitamin D Receptor Transactivation in Human Keratinocytes
Hairless protein can block vitamin D activation in skin cells.
research Complementary Evolution of Coding and Noncoding Sequence Underlies Mammalian Hairlessness
Both gene and non-gene areas of DNA evolved to make some mammals hairless.
research Whole Genome Sequencing Analysis of Alpaca Suggests TRPV3 as a Candidate Gene for the Suri Phenotype
The TRPV3 gene variant may cause the long-haired suri alpaca coat.
research Editor's Evaluation: Complementary Evolution of Coding and Noncoding Sequence Underlies Mammalian Hairlessness
Hairlessness in mammals is due to complex genetic changes in both genes and regulatory regions.
research Trichotillomania: What Do We Know So Far?
Trichotillomania treatment is most successful with a mix of behavioral therapy, medication, and social support.
research 4-O-Methylhonokiol Protects HaCaT Cells from TGF-β1-Induced Cell Cycle Arrest by Regulating Canonical and Non-Canonical Pathways of TGF-β Signaling
4-O-Methylhonokiol helps protect skin cells from growth-stopping effects of a protein by regulating growth-related pathways.
research Genome-Wide DNA Methylation and Transcriptome Analyses Reveal the Key Gene for Wool Type Variation in Sheep
The SOSTDC1 gene is crucial for determining sheep wool type.
research Other Questions on Basaloid Follicular Hamartoma
Basaloid follicular hamartoma's appearance can be similar to other skin conditions, and diagnosis should consider both the look and behavior of the tumor.
research Brain-Derived Nerve Factor and Neurotrophins in Androgenetic Alopecia
Lower growth factors linked to balding in androgenetic alopecia.
research Preservation of Stem Cells in Androgenetic Alopecia
Stem cells preservation in AGA could be a potential therapy, but more cases needed.
research Dissecting Folliculitis (Dissecting Cellulitis) of the Scalp: A 66-Patient Case Series and Proposal of Classification
Researchers found that dissecting folliculitis of the scalp is linked to obesity, severity increases with duration and number of nodules, and early treatment is important to prevent scarring.
research Adam10 Haploinsufficiency Causes Freckle-Like Macules in Hairless Mice
A mutation in the Adam10 gene causes freckle-like spots on Hairless mice.
research Bioengineering Skin Constructs
Future research should focus on making bioengineered skin that completely restores all skin functions.
research An Overview of Herbal Ingredients with Anti-Dandruff Activity in Shampoo Formulations
Some herbal ingredients like linalool and tea tree oil have anti-dandruff properties and are safe for use in shampoos.
research Building and Crossing the Translational Bridge: 2016 Alopecia Areata Research Summit Highlights
The summit aimed to speed up finding treatments for alopecia areata.
research Significance of Psychosomatic Factors in the Etiopathogenesis of Alopecia Areata
Psychological factors play a significant role in developing alopecia areata.
research Thyrotropin-Releasing Hormone Promotes Wound Re-Epithelialisation in Frog and Human Skin
Thyrotropin-Releasing Hormone helps heal wounds in frog and human skin.
research Lentiginosis Within Plaques of Linear Atrophoderma of Moulin: A Twin-Spotting Phenomenon?
The document suggests a rare skin condition might be caused by a genetic phenomenon.
research The Role of Histone Demethylases in Disease
Histone demethylases play a key role in the development of many diseases and may be targets for treatment.
research Hormonal and Genetic Etiology of Male Androgenetic Alopecia
research Quantification of the Vitamin D Receptor-Coregulator Interaction
Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.
research Partial Purification and Characterization of Two Distinct Types of Caspases from Human Epidermis
Two distinct caspases in human skin help with cell death and skin formation.
research Vitamin D and the Skin
research Reduced SMAD2/3 Activation Independently Predicts Increased Depth of Human Cutaneous Squamous Cell Carcinoma
Lower SMAD2/3 activation predicts more severe skin cancer.
research Platelet-Rich Plasma in Dermatology: New Insights on the Cellular Mechanism of Skin Repair and Regeneration
PRP helps skin heal, possibly through special cells called telocytes.
research Panax Ginseng Extract Antagonizes the Effect of DKK-1-Induced Catagen-Like Changes of Hair Follicles
Panax ginseng extract may help prevent hair loss caused by DKK-1.
research TGF-β and HSP70 Profiles During Transformation of Yak Hair Follicles from Anagen to Catagen Stage
TGF-β2 helps yak hair follicles enter the regression phase, while HSP70 tries to prevent it.
research Marine and Bovine-Derived Collagen Peptides Inhibit Catagen Development and Affect Stem Cells in Human Scalp Hair Follicles
Collagen peptides may help maintain hair growth and could be beneficial for hair loss conditions.