1 citations
,
December 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that manipulating Wnt/β-catenin signaling in embryonic mammary glands impacted their development, with high activity levels hindering branching and potentially redirecting cells toward hair follicle identity instead of mammary tissue.
1 citations
,
October 2022 in “Biomedicines” This study found that Prdm1 is crucial for whisker development in mice, affecting multiple signaling pathways and possibly playing a role in primates' evolutionary loss of vibrissae.
1 citations
,
June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that β-catenin stabilization in specific mammary epithelial lineages leads to cellular changes and the formation of hyperplastic lesions, revealing its role in initiating mammary neoplastic development.
1 citations
,
January 2020 in “Revista Brasileira de Ciência Veterinária” This case report describes a male cat with demodicosis primarily attributed to Demodex cati, suggesting the generalized disease may have been exacerbated by pruritus related to flea infestation.
1 citations
,
May 2024 in “Preprints.org” This study observed that age influences fur quality and hair follicle traits in Rex rabbits, with significant differences in the Wnt10b/β-catenin signaling pathways during hair follicle development, suggesting the ideal slaughter age should not be earlier than 120 days to maximize fur characteristics.
1 citations
,
March 2024 in “Cellular and Molecular Biology” In this study, researchers observed that Zibai ointment promoted chronic wound healing in rats by influencing the bFGF/Wnt/β-Catenin signaling pathway, demonstrating a higher wound healing rate compared to other treatments.
1 citations
,
December 2023 in “International journal of molecular sciences” In this study, researchers found that miR-199a-3p plays a regulatory role in hair follicle development via the PTPRF/β-catenin axis and established a mouse model of alopecia areata by downregulating this small RNA, suggesting its potential value in studying alopecia diseases.
1 citations
,
December 2023 in “Animals” In this study, researchers observed that the skin quality and hair follicle development of Rex rabbits improved when slaughtered in winter compared to summer, with findings suggesting seasonal regulation via multiple signaling pathways affecting fur characteristics.
1 citations
,
May 2023 in “Frontiers in Pharmacology” This study found that millet seed oil effectively promoted hair growth in a mouse model with testosterone-induced hair growth inhibition, suggesting its potential use in preventing or treating androgenetic alopecia.
1 citations
,
June 2021 in “Journal of pharmacopuncture” This study found that while CBD did not change gene expression including β-catenin in hair follicles, it restored decreased β-catenin expression in dermal papilla cells affected by testosterone or PMA, suggesting a potential modulating function on alopecia.
1 citations
,
May 2018 in “Tropical Journal of Pharmaceutical Research” This study found that low-fluence intense pulsed light promoted hair growth in C57BL/6 mice by inducing an earlier and prolonged anagen phase and activating the WNT/β-catenin pathway.
December 2025 in “Current Issues in Molecular Biology” In this systematic review, animal studies showed that cytarabine causes multi-organ toxicities, notably neurotoxicity, linked to oxidative stress and other mechanisms, though study quality raises concerns about reliability and translation to human outcomes.
October 2025 in “Buletin Veteriner Udayana” This case report described a young Himalayan kitten in Indonesia with notoedric mange, treated successfully with topical selamectin and sarolaner, highlighting the importance of early diagnosis and management to prevent reinfestation, especially in urban areas.
March 2025 in “Buletin Veteriner Udayana” In this study, a domestic cat diagnosed with scabiosis and Felicola subrostratus infestation was successfully treated with ivermectin, diphenhydramine, fish oil, sulfur soap, and topical fipronil, showing good treatment outcomes.
February 2025 in “Buletin Veteriner Udayana” In this case report, the 14-day treatment with ivermectin, sulfur baths, antihistamines, and supplements resulted in significant recovery in a cat with scabies and sporotrichosis, except for persistent alopecia on the ear pinna. The authors recommend maintaining a clean environment to prevent reinfection.
February 2025 in “Frontiers in Veterinary Science” This study found that keratin hydrolyzed, egg yolk lecithin, and fish collagen peptide promoted β-catenin nuclear translocation and increased gene expression related to hair regeneration in canine and cat skin cell lines, suggesting these nutrients may help improve hair regeneration in pets.
February 2025 in “Buletin Veteriner Udayana” In this study, therapy successfully resolved mite infections in a domestic cat, leading to improved skin and ear health, including reduced crusting and itchiness, and cleaner ears after 15 days.
This study introduced the C-CAT, a new assessment tool for central centrifugal cicatricial alopecia, and found that established treatments improved symptoms in most patients over six months.
January 2024 in “Arquivo Brasileiro de Medicina Veterinária e Zootecnia/Arquivo brasileiro de medicina veterinária e zootecnia” This study reports that treating a feline with progressive pruritus, alopecia, and FIV infection with imidacloprid and moxidectin resulted in remission of clinical signs and elimination of Demodex cati mites, as confirmed by parasitological examination and genetic sequencing.
In this review, the authors examined different surgical techniques for achieving brow lift effects, considering patient characteristics and goals to determine the most suitable approach for each case.
October 2023 in “Veterinary Science and Medicine Journal” In this case report, a 2-year-old cat with bilateral otitis externa and scabiosis was treated with a combination of antiparasitic, antibiotic, antifungal, and anti-inflammatory medications, leading to significant clinical improvement after 10 days.
August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that maintaining a low level of Wnt/β-catenin activity is crucial for mammary gland development, as excessive activity inhibits branching and promotes characteristics of hair follicles instead, highlighting its role in skin appendage identity decisions.
February 2023 in “Scientific Reports” This study suggests that cold atmospheric microwave plasma treatment may promote hair renewal by activating β-catenin and YAP/TAZ signaling in human dermal papilla cells.
This study identified ISX9 as a novel agonist of the Wnt/β‐catenin pathway, which promoted hair regrowth in mice and may offer a therapeutic approach for alopecia.
June 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that overexpression of β-catenin in bipotent Schwann-cell precursors promotes melanocyte development in limb areas by inducing MITF and repressing FoxD3, especially during a specific developmental timeframe.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study used a multi-layer in silico framework to evaluate Korean herbal compounds for androgenetic alopecia, identifying Biochanin A, Saponin Re, and Emodin as potential topical candidates with distinct safety and affinity profiles, although these findings remain purely computational without experimental validation.
July 2026 in “Journal of Investigative Dermatology” Tanshinone Capsule may help regrow hair by boosting specific cell signals.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated Korean herbal compounds in silico and identified Biochanin A, Saponin Re, and Emodin as potential topical treatments for androgenetic alopecia, each with specific safety and efficacy considerations.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, in silico analysis identified Saponin Re and Emodin as promising candidates for topical treatment of androgenetic alopecia, with Biochanin A having the most favorable safety profile among the tested compounds.
July 2026 in “Current Issues in Molecular Biology” This study found that Plerixafor, a CXCR4 antagonist, promotes melanogenesis in melanocytes by increasing MITF and tyrosinase expression and enhancing melanocyte migration, and it effectively restores pigmentation in a mouse depigmentation model without toxicity, highlighting its potential for treating pigmentary disorders.