59 citations,
February 2003 in “Veterinary Dermatology” Cyclosporin is effective for treating skin conditions in small animals, but requires careful dosing and monitoring for side effects.
58 citations,
March 2013 in “Human Reproduction Update” Products should be called 'sperm-safe' only after thorough, well-designed tests.
58 citations,
July 1986 in “Journal of The American Academy of Dermatology” Lowest effective minoxidil concentration is 1%, but 2% works better for male pattern baldness.
48 citations,
November 1992 in “International Journal of Dermatology” Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.
38 citations,
January 2014 in “International Journal of Endocrinology” Adrenal disorders can cause lasting brain and behavior issues in children.
35 citations,
January 2019 in “Clinics in Dermatology” Syphilis has a wide range of symptoms that can look like other diseases, and if not treated, it can progress to a more serious stage, especially in HIV-positive patients.
35 citations,
March 2012 in “Experimental and Clinical Endocrinology & Diabetes” The conclusion is that accurately identifying the cause of high androgen levels in women with PCOS is crucial and requires specific tests.
34 citations,
January 2008 in “International Review of Neurobiology” Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.
29 citations,
December 2017 in “Molecular therapy” Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.
25 citations,
November 2022 in “British journal of dermatology/British journal of dermatology, Supplement” Baricitinib for severe alopecia areata is generally safe, with common side effects like infections and acne, and low rates of serious complications.
21 citations,
October 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” A specific gene change plus an additional mutation in the same gene cause hereditary trichilemmal cysts.
21 citations,
April 2010 in “Veterinary Dermatology” Hydroxychloroquine showed some potential, but overall, the three drugs had limited success in treating lupus in dogs.
18 citations,
September 2021 in “Journal of Neuroendocrinology” Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.
17 citations,
June 2021 in “Molecules” Melatonin-loaded nanocarriers improve melatonin delivery and effectiveness for various medical treatments.
16 citations,
May 2020 in “Frontiers in pharmacology” Minoxidil can stop the growth of ovarian cancer cells without harming the heart.
16 citations,
May 1998 in “International Journal of Dermatology” Stress hormones like cortisol may trigger psoriasis flare-ups.
15 citations,
August 2021 in “Reviews in endocrine and metabolic disorders” COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.
13 citations,
November 2012 in “PubMed” 5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.
11 citations,
December 2010 in “Archives of Dermatology” A man with rare skin changes on his fingers was diagnosed with multiple myeloma-linked amyloidosis.
7 citations,
January 2001 in “PharmacoEconomics” The article concludes that a balance is needed between individual healthcare needs and societal resources when it comes to lifestyle drugs, with a call for compassionate policy application.
6 citations,
May 2022 in “Frontiers in physiology” Injecting CHIR-99021 into goose embryos improves feather growth by changing gene activity and energy processes.
6 citations,
January 2021 in “International Journal of Molecular Sciences” Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.
5 citations,
April 2021 in “Journal of Endocrinological Investigation” Higher DHT levels are linked to fewer hypogonadism symptoms in men with normal testosterone levels.
4 citations,
October 2020 in “Toxicology Mechanisms and Methods” Hesperidin protects rat testicles from finasteride damage and improves sperm health.
4 citations,
September 2020 in “Andrologia” Oregano extract helps fix testis and sperm damage caused by finasteride.
3 citations,
February 2017 in “Archives of Medical Science” Finasteride treatment changes Cx43 in rat testes, possibly causing fertility issues.
3 citations,
January 2016 in “Elsevier eBooks” Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.
2 citations,
September 2023 in “Curēus” Topical spironolactone may help treat ocular graft-versus-host disease with minimal side effects.
2 citations,
May 2020 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” Primary health care in Florianópolis mostly treated simple skin conditions, while secondary care handled more complex skin diseases.
2 citations,
January 2011 in “Elsevier eBooks” Early treatment of acne is crucial to prevent scarring and psychological effects.