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This study found that the compound M50054 inhibits apoptosis by blocking caspase-3 activation and may improve chemotherapy-induced alopecia and hepatitis symptoms.

In this study, researchers found that deleting Caspase-9 in hair follicle stem cells delayed apoptosis, leading to accelerated wound repair and new hair follicle regeneration by maintaining apoptotic cells as signaling centers.

In this study, short-term finasteride treatment reduced apoptotic factors caspase-7 and IGFBP-3 in prostate cancer cells but did not significantly affect androgen receptor expression compared to placebo.

In this study, finasteride treatment in men with androgenetic alopecia reduced the expression of caspases in hair follicles to levels similar to those in men with normal scalps.

This study investigated the role of NLRP3 inflammasomes in alopecia areata and found that outer root sheath cells may contribute to inflammation by increasing IL-1β and HMGB1 secretion when stimulated with double-stranded RNA.

This study reports that finasteride treatment in men with androgenetic alopecia appears to restore caspase and XIAP expression in hair follicles to levels similar to those in individuals without the condition.

This study found that intrinsic reactive oxygen species drive the hair follicle cycle progression through DNA damage and repair, apoptosis, and macrophage polarization, influencing hair loss and regeneration dynamics in mice.

This study found that high-dose radiation can induce accelerated cellular senescence, inflammation, and loss of epithelial stem cells in mouse and human skin, contributing to radiation dermatitis.

This study found that the Notch signaling pathway is suppressed in basal cell carcinomas and highly expressed in hair follicles, suggesting it might be a target for treatment strategies.

This study found that ruxolitinib modulated inflammatory changes and stimulated growth factor signals by blocking the JAK-STAT pathway in an in vitro model of alopecia areata.

This study found that minoxidil stimulates the Kir6.2/SUR2 potassium channel, leading to tumor growth arrest in an ovarian cancer xenograft model by disrupting mitochondrial function and inducing cell death.

This study found that diffuse alopecia in HIV-1-infected patients is characterized by higher rates of follicular stem cell apoptosis compared to controls, suggesting a hair cycle disturbance associated with the infection.

This study suggests that D-panthenol may promote hair growth by enhancing cell viability, suppressing apoptosis markers, and elongating the anagen phase in human hair follicle cells.

This study found that doxorubicin induces hair follicle apoptosis through TRAIL receptor signaling, providing insights for managing chemotherapy-induced hair loss.

This study reports that hair follicle-derived mesenchymal stem cells significantly reduced hair loss and inflammation in alopecia areata models, suggesting a potential therapeutic approach.

This study found that in yak hair follicles, TGF-β2 significantly contributes to the transition from growth to regression phases via inducing apoptosis, whereas HSP70 appears to inhibit follicle regression by protecting epithelial cells from apoptosis.

This study reports that A132, a hair dye ingredient, induces phototoxicity and photogenotoxicity via mitochondrial apoptosis when exposed to sunlight, suggesting potential risks of oxidative stress and hair damage.

This study found that topical formononetin treatment promoted hair regrowth in mice by normalizing hair follicle size and inhibiting apoptosis-related pathways.

Blocking cell death in certain stem cells can improve wound healing and tissue regeneration.

This study reports that a plant extract from Orobanche rapum can stimulate skin rejuvenation and protect cutaneous microbiota, potentially creating healthier skin.

Progranulin overexpression leads to shorter, thinner hair and increased cell death in mouse hair follicles.

In this study, male-derived brain tissue exhibited higher cell death following ischemia compared to female-derived tissue, and certain steroid hormones showed different neuroprotective effects depending on the sex of the tissue.

This study found that finasteride treatment in benign prostatic hyperplasia patients induced a transient, caspase-dependent apoptosis in epithelial cells, with activity peaking at 6-8 days and diminishing by 27-32 days.

This study found that silver nanoparticles biofabricated using Ostericum koreanum leaf extract inhibited inflammatory cytokine production in stimulated human mast cell lines, suggesting potential use in treating mast cell-mediated allergic diseases.

This study found that etifoxine pretreatment reduced neuroinflammation and improved cognitive function in LPS-induced neuroinflammation in mice, potentially through increased neurosteroid synthesis and reduced apoptosis.

In this study, umbilical cord mesenchymal stem cell-derived apoptotic extracellular vesicles were found to improve wound healing in type 2 diabetic mice by inhibiting macrophage pyroptosis and reducing oxidative stress levels.

This study found that TPA induces apoptosis in pig renal epithelial cells by affecting cell cycle proteins, and activated ras can prevent this process.

This study found that vitamin A significantly enhanced the proliferation and inhibited apoptosis of rabbit dermal papilla cells under heat stress, likely by modulating miR-195/IGF1 and Wnt10b/β-catenin signaling pathways.

This study found that ethanolic asiasari radix extract may induce apoptosis in G361 melanoma cells through ROS-dependent regulation of p53, suggesting potential as a medicinal option for melanoma.

In this animal study, combined cellular therapy significantly improved diabetic wound healing, and probiotics further enhanced these effects by reducing oxidative stress, apoptosis, and inflammation while promoting vascularization and collagen organization.