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Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

The dermal regeneration template is effective in skin regeneration, reducing scarring, and has potential for future improvements.

Chitosan/LiCl composite scaffolds help heal deep skin wounds better.

The hydrogel with silver and mangiferin helps heal wounds by killing bacteria and aiding skin and tissue repair.

Bioactive molecules show promise for improving skin repair and regeneration by overcoming current challenges with further research.

Using skin stem cells and certain molecules might lead to scar-free skin healing.

Hair follicles and deer antlers regenerate similarly through stem cells and are influenced by hormones and growth factors.

Using gelatin sponges for deep skin wounds helps bone marrow cells repair tissue without scarring.

Exosomes show promise for future tissue regeneration.

Electrospun matrices help regenerate skin and hair follicles using PCL and collagen scaffolds.

The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.

Scientists made working hair follicles using stem cells, helping future hair loss treatments.

Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.

EVAL membranes help create cell structures that can regrow hair follicles.

Cell-based therapies using dermal papilla cells and adipocyte lineage cells show potential for hair regeneration.

PI3K/Akt pathway is crucial for hair growth and regeneration.

The African spiny mouse can fully regenerate its muscle without scarring, unlike the common house mouse.

Scientists have created a method to deliver specific cells that can regenerate hair follicles, potentially offering a new treatment for hair loss.

Nanofiber structure helps regenerate hair follicles.

The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.

Scaffold improves hair growth potential.

The hydrogel with bioactive factors improves skin healing and regeneration.

Scientists created three types of structures to help regrow hair follicles, and all showed promising results for hair regeneration.

Peptide hydrogel scaffolds help grow new hair follicles using stem cells.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Fat cells are important for tissue repair and stem cell support in various body parts.

MSC-protein helps regenerate gum tissue and bone.

Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.