February 2020 in “İstanbul medical journal” This study evaluated the effects of metformin, ethinyl estradiol/cyproterone acetate (EE/SA), and their combination on carotid intima-media thickness and various cardiovascular markers in patients with polycystic ovary syndrome.
September 2023 in “Journal of the turkish academy of dermatology” In this study, researchers found that men with androgenetic alopecia had higher obesity-related parameters, such as fat percentage and BMI, compared to healthy controls, but observed no differences in cardiovascular markers like CIMT and EFT.
January 2015 in “Ankara Üniversitesi Tıp Fakültesi mecmuası” In this study, patients with advanced androgenetic alopecia stages had higher carotid intima media thickness and worse aortic elasticity, suggesting a potential link to subclinical atherosclerosis.
9 citations
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February 2019 in “Journal of Clinical Research in Pediatric Endocrinology” In this study, children with classical congenital adrenal hyperplasia were found to have increased epicardial fat thickness, which was associated with subclinical atherosclerosis markers and left ventricular dysfunction, especially in poorly controlled cases.
16 citations
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January 2013 in “Internal Medicine” This study found that premature hair whitening intensity is independently associated with increased carotid artery intima-media thickness, suggesting a link between hair whitening and cardiovascular risk.
38 citations
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February 2009 in “Journal of The European Academy of Dermatology and Venereology” This study found that patients with severe vertex pattern androgenetic alopecia had significantly higher carotid intima-media thickness, suggesting an increased risk of subclinical atherosclerosis compared to other alopecia patterns and healthy controls.
2 citations
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April 2023 in “Pharmaceuticals” This review discusses the controversial cardiovascular safety and efficacy of subcutaneous testosterone therapy in postmenopausal women, noting that its long-term use appears safe, but CV risk assessments remain disputed.
January 2025 in “Dermatologic Therapy” In this study, AA patients and healthy controls showed no significant difference in carotid intima-media thickness, but AA patients had higher diastolic blood pressure and fasting blood glucose levels, indicating potential cardiovascular risks.
January 2016 in “Ankara Üniversitesi Tıp Fakültesi mecmuası” Severe hair loss (androgenetic alopecia) is linked to higher risk of heart disease (cardiovascular atherosclerosis).
April 2020 in “Journal of the Endocrine Society” This study found that among transgender men undergoing long-term testosterone therapy, a severe pattern of androgenetic alopecia may indicate increased arterial stiffness, as measured by higher intima-media thickness of the carotid artery.
1 citations
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May 2013 in “Journal of the Egyptian Women's Dermatologic Society (Print)” In this study, women with androgenetic alopecia showed higher cholesterol levels and carotid artery thickness, suggesting a potential link between female AGA and cardiovascular disease.
2 citations
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November 2016 in “PubMed” In this study, lichen planus was associated with increased carotid intima media thickness, especially with longer disease duration, but was not an independent predictor of this condition.
June 2016 in “American Journal of Cardiology” This paper discusses the relationship between androgenetic alopecia and cardiovascular atherosclerosis, focusing on carotid intima-media thickness and the SYNTAX score, and reports no new results.
February 2023 in “Benha Journal of Applied Sciences” Among male patients with androgenetic alopecia, this study found that serum endocan levels were lower compared to controls, but no significant difference in carotid intima-media thickness was observed between groups.
October 2018 in “Journal of Clinical Research in Pediatric Endocrinology” This study found that children with classic congenital adrenal hyperplasia had elevated epicardial fat thickness, which was associated with increased carotid intima media thickness, left ventricular mass, and mitral deceleration time.
24 citations
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January 2015 in “International Journal of Trichology” This research observed that among young men with androgenic alopecia, there was a significant association with metabolic syndrome compared to healthy controls, suggesting AGA as a potential early marker for metabolic risk.
June 2026 in “Preprints.org” This study found that in healthy young men, oral minoxidil at 5 mg/day led to increased carotid intima-media thickness and vascular aging, suggesting potential cardiovascular side effects at higher doses. A dose-dependent effect was observed, while dutasteride displayed a favorable vascular profile without significant changes.
44 citations
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May 2008 in “Fertility and Sterility” In this study, young, nonobese PCOS patients showed significant insulin resistance, but no significant difference in endothelial function compared to healthy controls, suggesting other factors may influence endothelial health.
5 citations
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July 2016 in “Journal of Clinical Hypertension” This study found that hypertensive patients with severe androgenic alopecia exhibited impaired coronary microcirculation, suggesting they may face increased cardiovascular risk.
October 2013 in “Journal of the American College of Cardiology” This study investigates the potential link between atrial fibrillation and circulating aldosterone levels related to cardiac fibrosis in patients with hypertension.
24 citations
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January 2012 in “Journal of Cellular Biochemistry” This study found that C-reactive protein may enhance monocyte adhesion to endothelial cells through NOX-mediated oxidative stress, suggesting a potential mechanism for atherogenesis.
March 2014 in “Fertility and Sterility” The April 2014 issue of "Fertility and Sterility" discussed various reproductive health topics, including hormone therapy benefits, sperm and genetic factors in male infertility, and the link between PCOS and diabetes.
155 citations
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March 2006 in “The American Journal of Medicine” This study found that young women with polycystic ovary syndrome have altered endothelial function associated with insulin resistance and lower adiponectin levels.
13 citations
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November 2015 in “Blood Pressure” This study found that early-onset androgenetic alopecia, especially with a vertex pattern, may be an independent risk factor for cardiovascular disease and metabolic syndrome in men.
January 2017 in “Journal of clinical & experimental dermatology research” This study found no significant difference in carotid intima-media thickness between individuals with androgenetic alopecia and control subjects.
May 2023 in “Journal of Cosmetic Dermatology” This study found that AGA patients had higher serum and epidermal irisin levels, which were associated with metabolic syndrome, dyslipidemia, and abnormal carotid intima media thickness, suggesting potential irisin resistance affecting cardiometabolic health.
44 citations
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October 2011 in “Gynecological Endocrinology” This review discusses the effects of oestrogen on skin ageing and highlights the need for large-scale clinical trials to evaluate postmenopausal oestrogen use, reporting no new findings.
4 citations
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January 2016 in “Annals of Dermatology” This study found that men with more advanced androgenetic alopecia had increased epicardial fat thickness, suggesting a potential link to coronary risk.
90 citations
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February 2013 in “The Journal of Clinical Endocrinology and Metabolism” This study found that women with polycystic ovary syndrome have higher global adiposity and increased visceral fat, particularly in the ip and mesenteric depots, compared to women without androgen excess.
20 citations
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February 2004 in “Clinical and Experimental Ophthalmology” This paper presents two cases of rare intraorbital ophthalmic artery aneurysms associated with arteriovenous malformations and discusses their clinical presentation, pathogenesis, and management, but reports no new clinical outcomes.