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Terbinafine is more effective than itraconazole for toenail fungus, especially in older patients, and debridement improves its effectiveness.

Not all nail problems are caused by fungus, new allergens are being identified, PCOS has various treatments, and aesthetic procedures like Botox are advancing.

Doctors should recognize various nail disorders, new allergens, and metabolic syndrome in patients, and use botulinum toxin carefully in aesthetic procedures.

Hair loss can indicate brain aging and potential small vessel disease, but more research is needed to understand the clinical impact.

PCOS affects a similar percentage of Black and White women in the Southeastern United States.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

Polycystic ovary syndrome is found in 6.5% of unselected Caucasian women in Spain.

PCOS affects about 4% of women in the southeastern U.S. equally across Black and White populations.

About 6.5% of young Caucasian women in Spain have polycystic ovary syndrome.

Eclipta alba extract improved learning, memory, and stress-related ulcers in rats without affecting movement or causing anxiety.

Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Lower SHBG levels may increase the risk of PCOS.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

Doctors need to be better prepared to assess and treat obesity in patients.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Some parents have a mild form of congenital adrenal hyperplasia without symptoms, and they usually don't need treatment.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

People with polycystic ovary syndrome have a higher chance of having chronic thyroiditis.

SHBG may be a useful early indicator and treatment target for PCOS.

Patients with Bohring-Opitz syndrome and ASXL1 mutations need regular kidney ultrasounds to check for tumors.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Certain microRNAs in the fluid around eggs are linked to Polycystic Ovary Syndrome and may help diagnose it.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Women with PCOS are more likely to have fatty liver disease, especially if they have metabolic problems.

Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Women with PCOS are more likely to have insulin resistance and obesity, especially those with the most severe type I PCOS.