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Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Women with polycystic ovary syndrome tend to have a longer distance between the clitoris and anus.

Female hair loss linked to metabolic syndrome, not in males.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

Chromium supplements don't improve insulin, hormone levels, or cholesterol in women with PCOS but raise testosterone levels.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Male pattern baldness involves hormone-related hair thinning, shorter hair, and inflammation.

Genomic approach finds new possible treatments for hair loss.

Inhalation therapy may repair and protect elastin in the lungs of COPD patients.

The method can measure vitamin B3 levels in human hair accurately.

People with hidradenitis suppurativa often have lower vitamin D levels, weaker hip bones, and altered bone metabolism markers.

PCOS is linked to diabetes and insulin resistance, and managing AGEs may help treat related symptoms.

Phytotherapeutic compounds and supplements can help manage Polycystic Ovarian Syndrome (PCOS).

Lower LDL-c levels predict higher COVID-19 mortality.

848 genes related to fat and metabolism are less active in people with Central Centrifugal Cicatricial Alopecia.

Modified HDL can better deliver drugs and genes, potentially improving treatments and reducing side effects.

Sleep problems and skin issues affect each other; poor sleep can worsen skin conditions, and some skin treatments can improve or harm sleep quality.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

Hair loss needs more research for better treatments.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

JAK inhibitors help with skin conditions but need more research on dosing and safety.

Six new genetic regions linked to early hair loss also connect to Parkinson's disease and prostate cancer, possibly leading to new treatments.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

AR polyglycine repeat doesn't cause baldness.

Doctors should know how to diagnose and treat PCOS, which often involves checking for high male hormone levels and using medications to manage symptoms.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

Selenium might help with insulin resistance and cholesterol in PCOS, but more research is needed to confirm its benefits.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.