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The 2023 guideline advises a detailed approach for PCOS, focusing on early detection, lifestyle and medical treatments, and managing health risks.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.

The patient with autoimmune hypothyroidism improved after treatment for thyroid and associated conditions.

Minoxidil improves blood flow and vessel flexibility, potentially helping with vascular stiffness.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

PCOS is a common hormonal disorder in women, marked by symptoms like hair growth and menstrual issues, and requires personalized treatment.

People with psoriasis are more likely to have Metabolic Syndrome than those without psoriasis.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Finasteride helps reduce heart enlargement in heart failure patients.

Finasteride causes temporary cell death in BPH tissues.

Testosterone reduces heart damage and inflammation after injury.

Tofacitinib, a JAK inhibitor, improved hair regrowth in most patients with severe alopecia areata and had minimal side effects.

Women with PCOS should have an oral glucose tolerance test for effective diabetes screening.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Finasteride helps reduce heart issues and improves heart function.

Mice with autoimmune hair loss showed signs of heart problems.

Taking both finasteride and dutasteride for prostate issues may raise the risk of heart problems.

The man's fatigue and erectile dysfunction were improved by treating his obesity-related low testosterone without needing testosterone replacement.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

Excessive selenium from a supplement caused toxicity but patients recovered with care.

New treatments for male hypogonadism are effective and should be personalized.

There is no clear recommendation for using selenium in cancer patients; it may be beneficial to correct low selenium levels before treatment.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.

Certain diets can affect skin conditions, but more research is needed to understand these relationships fully.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Most treatments for spondyloarthritis are safe, but monitoring and careful selection based on patient risks are important.

Vitamin D deficiency is common in women with PCOS and linked to some metabolic problems, but not the main cause of their metabolic issues.