research Evaluation of Cardiac Risk Marker Levels in Obese and Non-Obese Patients with Polycystic Ovaries
Obese and non-obese women with PCOS have higher heart risk markers, especially if they are obese.
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research Is Polycystic Ovary Syndrome a Sexual Conflict? A Review
The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.
research Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D2 Synthase as a Multifunctional Lipocalin
Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
research Vitamin D Activates Type A Natriuretic Peptide Receptor Gene Transcription in Inner Medullary Collecting Duct Cells
Vitamin D boosts a specific gene activity in kidney cells that could improve heart and kidney function.
research Basic Mechanisms of SARS-CoV-2 Infection: Implications for Endocrine Systems
SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.
research Anti-Androgenic Therapy with Finasteride Improves Cardiac Function, Attenuates Remodeling, and Reverts Pathologic Gene Expression After Myocardial Infarction in Mice
Finasteride improves heart function and repairs damage after heart attack in mice.
research Potential Involvement of the Stem Cell Factor Receptor c-kit in Alopecia Areata and Androgenetic Alopecia: Histopathological, Immunohistochemical, and Semiquantitative Investigations
c-kit affects hair growth and color in alopecia areata and androgenetic alopecia.
research Extra Virgin Olive Oil as Nutritional Therapeutic Immune Enhancer
Extra virgin olive oil may boost the immune system and help fight infections like COVID-19.
research Stimuli-Responsive Nanoformulations for CRISPR-Cas9 Genome Editing
Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.
research Benign Prostatic Hyperplasia, Metabolic Syndrome, and Androgenic Alopecia: Is There a Possible Relationship?
People with early hair loss may have a higher chance of enlarged prostate and metabolic syndrome, so they should be checked for urinary and metabolic issues.
research Rational Investigations in the Diagnosis and Management of Women with Hirsutism or Androgenetic Alopecia
Diagnose and manage hair issues in women by checking medical conditions and using personalized treatments.
research Male Pattern Baldness: Psychological Impact, Disease Association, and Treatment Options
Male pattern baldness is often genetic and linked to a hormone, with treatments like finasteride and minoxidil being effective for some men.
research In-Silico Cardiac Aging Regulatory Model Including MicroRNA Post-Transcriptional Regulation
Researchers created a model to understand heart aging, highlighting the role of microRNAs and identifying key genes and pathways involved.
research The Conception and Evaluation of Sexual Health Literature
The document concludes that better research methods are needed in men's sexual health to provide stronger evidence and improve patient care.
research Ethnobotanical Study of Endemic and Non-Endemic Medicinal Plants Used by Indigenous People in Environs of Gullele Botanical Garden Addis Ababa, Central Ethiopia: A Major Focus on Asteraceae Family
Local healers in Addis Ababa use 81 medicinal plants, mainly from the Asteraceae family, to treat skin and general diseases, with Echinops kebericho being an endangered plant important in their practices.
research Acne
Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.
research Hidradenitis Suppurativa, Acne Inversa, Dissecting Terminal Hair Folliculitis
Hidradenitis Suppurativa is a chronic skin condition best treated early with surgery for better outcomes and less recurrence.
research Sexual Dysfunction, Including Hypoactive Sexual Desire Disorder: Diagnosis and Treatment Recommendations
Testosterone therapy can improve sexual function in women but long-term safety is unclear.
research Approaching Erectile Dysfunction in Dermatology Patients
Dermatologists should address erectile dysfunction in patients with skin conditions to improve their quality of life.
research Nurses' Drug Alert: Findings and Updates from April 1987
Some drugs can cause serious side effects, like hypoglycemia from mix-ups, skin reactions, or depression, and while penicillamine may help rheumatoid arthritis more than auranofin, it has more severe side effects.
research Alopecia Areata and Vitamin D3 Deficiency: The Potential of Calcipotriol as a Treatment
Calcipotriol's effectiveness for treating alopecia areata is unclear and needs more research.
research Vitamin D and Skin: A Review and Update
Vitamin D is important for skin health and can help treat and prevent various skin conditions.
research Case Report: A Novel Splice-Site Mutation of MTX2 Gene Caused Mandibuloacral Dysplasia Progeroid Syndrome: The First Report from China and Literature Review
A new MTX2 gene mutation caused a severe genetic disorder in a young Chinese girl.
research Distinguishing Gender Identity From Biological Sex in Dermatologic Health Care: Methods, Harms, and Paths Forward
Accurate gender and sex assessment in dermatology is essential for respectful and precise patient care.
research Polycystic Ovarian Syndrome Revisited
PCOS is a complex condition that affects women's hormonal balance and metabolism, requiring lifestyle changes and medical management.
research Myotonic Dystrophy Type 1: Enhancing Patient Management Through Genetic and Multisystem Studies
There is no cure for myotonic dystrophy type 1, so treatment focuses on managing symptoms and complications.
research Trend and Co-Occurrence Network of COVID-19 Symptoms From Large-Scale Social Media Data: Infoveillance Study
Social media data can help track and predict COVID-19 symptoms and trends.
research Reply to Comment on: The Gabrin Sign
Men with male pattern baldness may be more at risk for severe COVID-19, and anti-androgen treatments could offer protection.
research Acne Protection: Measures and Miseries
Acne can be managed with various treatments and requires psychological support due to its emotional impact.
research Mixing the Old with the New: Drug Repurposing for Immune Deficiency in the Era of Precision Medicine and Pediatric Genomics
Using old drugs for new uses can help treat rare immune deficiencies.