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Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

Low-dose finasteride may cause lasting sexual dysfunction and suicidal thoughts in young men.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

Insulin resistance linked to obesity may increase COVID-19 severity.

Psoriasis is linked to other autoimmune diseases and involves a specific inflammatory process.

A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.

COVID-19 might affect male fertility, but more research is needed to understand the full impact.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Minoxidil is mostly safe, but high doses can cause electrolyte imbalances and heart issues in dogs.

Fat cells are important for tissue repair and stem cell support in various body parts.

Topical minoxidil effectively treats male pattern baldness and prevents hair loss.

PDGF signaling is crucial for maintaining and renewing hair follicle stem cells, which could help treat hair loss.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.

NSAIDs may not affect soft tissue healing but should be used carefully for bone fractures and more research is needed to understand sex differences in response.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

In Brazil in 2018, the most common skin issues were acne, photoaging, and nonmelanoma skin cancer, with treatments often including topical medications and sunscreen.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Suppressing certain hormones might help prevent prostate cancer.

Grey hair and baldness may be linked to COVID-19 severity, but more analysis is needed; post-infectious hair loss is related to the severity of the disease and usually recovers within 3-6 months.

The document concludes that there is a significant lack of reporting on the sex and age of cells in skin research, which could affect clinical trials and treatments.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

Minoxidil promotes hair regrowth, but more research needed for effectiveness and response factors.

Newer low-dose oral contraceptives with less androgenic effects improve patient compliance.

Looking at skin can help find and treat serious diseases early.