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Orphan drug benefit scores in Germany are influenced by phase III data and lack of alternatives, but not linked to price or discounts.

Polycystic ovary syndrome is a complex condition that affects women's mental, reproductive, and metabolic health throughout their lives.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

No cure for female pattern hair loss, but various effective treatments exist.

PCOS symptoms change with age; younger women have higher androgen levels and less metabolic issues, while older women face more metabolic challenges despite milder PCOS symptoms.

Obese people have more skin problems like stretch marks and infections, which get worse with higher obesity levels.

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

Having a lot of gray hair and hair loss are linked to more severe COVID-19.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Simvastatin/ezetimibe did not effectively treat severe alopecia areata and caused side effects in some patients.

Recognizing and treating early signs of insulin resistance can help prevent type 2 diabetes and improve life quality.

COVID-19 patients may experience hair loss, but it's not linked to their age or sex.

Extra virgin olive oil may boost the immune system and help fight infections like COVID-19.

Narrowband UVB treatment increases certain gene expressions in psoriasis skin and improves symptoms.

The conclusion is that certain genetic factors and blood types may affect COVID-19 severity, but changes in ACE2 and TMPRSS2 genes are not clearly linked to it.

Diagnosing Polycystic Ovary Syndrome is hard due to varying symptoms, no set criteria, and the need for better tests and education.

WS PRO 160 I 120 mg effectively treats urinary symptoms from BPH with good safety and tolerability.

More research is needed to find effective treatments for sickle cell disease-related priapism.

Women with PCOS are at higher risk for gum disease, and managing shared risk factors can help both conditions.

Gingivitis may increase a hormone linked to ovarian function in women with a certain ovary condition, and treating gum disease could help manage it.

Managing PCOS effectively requires focusing on psychological health, lifestyle changes, and medication.

PCOS is a hormonal disorder causing infertility and menstrual problems, often linked to obesity and can lead to acne, treated with hormonal and insulin-sensitizing medications.

Terbinafine is more effective than itraconazole for toenail fungus, especially in older patients, and debridement improves its effectiveness.

Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.

Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.