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This article discusses the hair cycle of mice and its relevance in studying experimental carcinogenesis sequences, but it reports no new research findings.

This study suggests that activation of polyamine catabolism in K6-SSAT transgenic mice may significantly increase skin tumor development and progression to carcinomas following chemical induction.

This study found that androgen receptor inactivation in male and female mice reduced susceptibility to DMBA-induced skin cancer, but the effect varied by the carcinogenesis model.

This study found that enzyme activity related to cancer induction by polycyclic aromatic hydrocarbons can be increased by using a shampoo containing crude coal tar and significantly inhibited by imidazole compounds in human hair follicles.

This review by two dermatologists suggests that hair on the human scalp may protect against skin cancer not just physically, but by enabling IL-17 immune surveillance, with hair loss potentially leading to increased tumor growth due to reduced immunosurveillance.

In this review, the authors propose that hair on the scalp may protect against non-melanoma skin cancer by maintaining an IL-17 biased immunosurveillance, with hair loss potentially increasing the risk of skin cancer due to disrupted immune monitoring.

The study observed that the tumor suppressor activity of bone morphogenetic proteins in mouse skin epithelium depends on Noggin levels, inhibiting Wnt and Shh signaling pathways to prevent tumor initiation and progression.

This study found that the K6/ODC transgenic mouse model is highly sensitive to identifying genotoxic carcinogens, showing 100% concordance with traditional rodent bioassays.

This study found that dimethylarsinic acid significantly accelerates skin tumor development in hair follicle-targeted K6/ODC transgenic mice.

This study reports that actively proliferating Lgr5+ stem cells in hair follicles do not appear to drive tumor formation in experimental skin carcinogenesis.

This study found that Bcl-xL deficiency in mice increased apoptosis and resistance to skin tumor development, highlighting Bcl-xL's role in early skin carcinogenesis through anti-apoptotic functions.

This study found that mice genetically modified to overexpress the serine protease inhibitor hurpin showed reduced UV-induced apoptosis but increased susceptibility to skin cancer after chemical carcinogenesis.

This study found that overexpressing the PML protein in transgenic mice decreased skin tumor occurrence and delayed their progression, highlighting PML's potential role in influencing keratinocyte growth and differentiation.

In this study, mice lacking podoplanin in epidermal keratinocytes showed reduced tumor cell invasion and peritumoral lymphangiogenesis, suggesting that keratinocyte-expressed podoplanin contributes to advanced stages of skin tumor progression.

This study found that Lgr6+ stem cells in mice are not major initiators of UV- or chemically induced skin tumors.

This study observed that K5Cre +/+ transgenic mice develop a distinct phenotype characterized by wavy hair, curly whiskers, and an increased rate of papilloma malignant transformation.

In this review, the authors discuss how hair may protect against scalp skin cancer by enabling IL-17-biased immunosurveillance, while hair loss could permit tumor development by reducing this immune protection.

In a mouse model study, researchers observed that the absence of MCPIP1 in myeloid cells decreased susceptibility to chemically induced skin papillomas but caused significant hair loss and skin pigmentation changes, suggesting a role for MCPIP1 in skin carcinogenesis and follicle integrity.

This research concluded that Snail2's absence in myeloid progenitors promotes tumor progression in mice, and specific zinc fingers are crucial for Snail1 and Snail2's roles in establishing epithelial-to-mesenchymal transition.

This review discusses the preclinical findings on cyproterone acetate and suggests that while it has a low potential cancer risk for patients, its tumor effects in female rats may involve both genotoxic and mitogenic mechanisms.

This review discusses the potential carcinogenic effects of anabolic androgenic steroids, particularly regarding Leydig cell tumors, and highlights the need for preventive information campaigns due to associated health risks.

In this study, Brca1(S971A/S971A) mice showed a moderately increased risk of spontaneous tumor formation and defects in DNA damage response, suggesting CHK2 phosphorylation of BRCA1 is crucial for tumor suppression.

This study found that mice with a mutation in the Zdhhc13 gene exhibited increased susceptibility to skin cancer, highlighting a potential protective role of palmitoyl acyltransferase in skin carcinogenesis.

This study found that carcinogen-treated skin grafts in mice developed tumors depending on the graft's thickness and the site of transplantation, suggesting the role of both factors in tumor formation.

This study found distinct skin surface changes, including faint mosaic melanoderma and atypical scaliness, on long-standing sun-exposed balding scalps that may be associated with actinic field carcinogenesis.

In this study, jute-batching oil did not cause cancer in mice, but it shortened the time to tumour development when combined with a known carcinogen, indicating potential cancer-promoting activity.

This study concluded that there was clear evidence of carcinogenic activity of C.I. Acid Orange 3 in female F344/N rats but not in male rats or B6C3F1 mice of either sex.

This protocol details a method for inducing skin cancer in mice through chemical carcinogenesis, which studies cutaneous malignancies but does not report new findings.

This study explores the role of cell competition in maintaining genomic quality in epidermal stem cells and proposes that this process might influence cancer development in skin tissues.