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Liver transplantation is a viable option for children with propionic acidemia, improving quality of life and diet, but does not remove all risks and long-term brain outcomes are uncertain.

Genetically modified plants could be an important source of omega-3 fats to meet global needs.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.

FLRG and follistatin have different roles in wound healing.

New research on prostamide F2α has led to treatments for glaucoma and eyelash growth and may have more medical uses.

Vitamin D3 can help improve hair growth by enhancing the function of specific skin cells and could be useful in hair regeneration treatments.

L-cysteine slows down the breaking of bonds in hair due to electrostatic interactions.

The study found that variations in hair protein genes are likely due to evolutionary deletions or duplications.

Minoxidil in HA-PLGA nanoparticles effectively treats alopecia through skin delivery.

VDUP1 is found in skin and hair follicles, interacts with sciellin, and may help regulate skin cell differentiation.

The compound (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile can stimulate hair growth and reduce oil production when applied topically.

Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.

The R343H mutation in the VDR gene causes vitamin D-resistant rickets with alopecia by impairing specific gene activity.

Hair loss is significantly linked to lower levels of certain genes in hair follicles.

Finding functions for unknown GPCRs is hard but key for making new drugs.

Tissue-derived extracellular vesicles are crucial for cancer diagnosis, prognosis, and treatment.

Keratin hydrogels from human hair show promise for tissue engineering and regenerative medicine.

Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.

A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.

A special dressing called FEA-PCEI can speed up wound healing, reduce scars, and help grow new hair follicles, but only at the right dosage.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

The new skin patch with human matrix and antibiotic improves wound healing.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.