November 2019 in “International journal of research in Ayurveda and pharmacy” In this case report, a 35-year-old male experiencing hair loss showed improvement with new hair growth after receiving Ayurvedic Rakta Mokshana therapy, including Pracchana and Cupping, within 15 days.
1 citations
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May 2024 in “AYUSHDHARA” This case report details a patient with alopecia areata treated with wet cupping and Ayurvedic Rasayan therapy, observing complete hair regrowth in two bald patches after a month of treatment.
5 citations
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November 2023 in “Journal of Ayurveda and Integrative Medicine” In this study, a case of Alopecia totalis was treated using cupping therapy along with ayurvedic treatments, suggesting that the combination may be effective due to the herbs' synergistic effects and cupping's immunostimulant activity.
September 2020 in “Journal of the turkish academy of dermatology” In this study, 13.3% of dermatology patients reported using traditional and complementary medicine, with herbal remedies being the most common method, especially among middle-aged university graduates.
2 citations
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March 2024 in “Supportive Care in Cancer” In this study, manual cold capping was found to be effective in minimizing chemotherapy-induced alopecia, with 92.1% of patients retaining 50% or more of their hair, although effectiveness varied with different chemotherapy regimens.
15 citations
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January 2013 in “Dermatologic Surgery” This study observed that white hair follicles in vitiligo patients may repigment following epithelial grafting and phototherapy, suggesting potential cosmetic improvements in vitiligo treatment.
January 2025 in “Indian Journal of Unani Medicine” This case study observed that hijāmah bil shart (wet cupping) led to significant improvements in hair texture, reduced shedding, and overall scalp health in a 34-year-old male with androgenetic alopecia, with no adverse effects.
45 citations
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January 2016 in “Journal of Nanomaterials” In this study, silver nanoparticles derived from Ziziphus nummularia leaf extract showed enhanced antibacterial, antifungal, antioxidant, and hair growth properties compared to the leaf extract itself.
October 2022 in “Hair Transplantation” This chapter outlines the sequential steps for using motorized follicular unit extraction machines with blunt punches in hair restoration, noting their advantages in minimizing follicle transection and providing tactile feedback.
14 citations
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August 2014 in “The FASEB Journal” This study found that the catalytically inactive serine protease CAP1/Prss8 can still induce skin disorders in mice and is subject to inhibition by nexin-1, independent of its catalytic activity.
107 citations
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April 2014 in “The Plant cell” In this study, researchers showed that the CAP1 gene regulates root hair growth in plants by modulating cytoplasmic ammonium levels and maintaining calcium gradients, highlighting its role in ammonium homeostasis.
3 citations
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August 2018 in “Journal of Structural Biology” KAP8.1 protein is crucial for hair structure and interacts with keratin 85.
51 citations
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January 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified a novel keratin-associated protein, KAP24.1, which is specifically expressed in the human scalp and located in the hair cuticle.
5 citations
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October 2022 in “Biology” This study found that CAP1 plays a significant role in reducing ammonium toxicity in Arabidopsis thaliana by promoting shoot growth and maintaining reactive oxygen species homeostasis.
62 citations
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January 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified 16 novel high sulfur KAP genes and two KAP pseudogenes on chromosome 21q23, showing expression in a specific region of the hair fiber cuticle.
16 citations
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January 2017 in “Physical chemistry chemical physics/PCCP. Physical chemistry chemical physics” This study presents computational modeling and experimental analysis of the HGT protein KAP8.1, identifying key structural features that may influence hair's response to environmental conditions.
226 citations
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January 2006 in “International review of cytology” Keratin-associated proteins are crucial for hair strength and structure.
28 citations
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December 2015 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that prostasin's proteolytic activity is necessary for normal hair follicle development in mice, but not for interfollicular epidermal development.
5 citations
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March 2017 in “Gene” This study found that the transcription factor CAP1 negatively regulates KRT83 expression in Tan sheep, possibly influencing their curly hair phenotype.
46 citations
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June 2013 in “Journal of structural biology” This study suggests that the mechanical robustness of hair may be enhanced by the binding interactions of keratin-associated proteins, particularly KAP8.1, with intermediate filament proteins.
3 citations
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February 2018 in “Experimental and Molecular Medicine/Experimental and molecular medicine” This study suggests that hair loss disorders like Marie Unna hereditary hypotrichosis may result from mutations that disrupt post-transcriptional regulation of HR protein expression by PCPB2 interacting with Hr mRNA.
In this study, researchers observed that IRES/Cap translation initiation increased during caloric stress across cell differentiation states and also unexpectedly rose during normal differentiation processes in mice, with lower IRES/Cap being linked to higher stem cell potential, mediated by PTBP1, a RNA processing protein.
24 citations
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October 2019 in “Genes” In this study, the identification of a novel KAP gene in sheep, named KRTAP36-1, was associated with increased prickle factor in wool, suggesting its potential as a genetic marker for breeding purposes.
9 citations
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September 2013 in “Journal of Applied Animal Research” This study identified eight alleles of the caprine KAP13-3 gene in cashmere goats, which could influence gene expression and cashmere fiber characteristics.
98 citations
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June 2001 in “Journal of biological chemistry/The Journal of biological chemistry” This study identified a cluster of genes on chromosome 17 related to hair keratin-associated proteins, including 37 genes forming seven multigene families, localized in the hair shaft's upper cortex.
8 citations
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March 2004 in “Mammalian genome” KAP genes are crucial for hair development and show both shared and unique traits in humans, chimpanzees, and baboons.
92 citations
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January 2012 in “International Journal of Biological Sciences” This article proposes an updated naming system for keratin-associated proteins and genes, aiming to improve data storage and retrieval by including species information and genetic variation.
26 citations
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March 1995 in “Differentiation” This study isolated and sequenced the complete gene rKAP4L1, which encodes a cysteine-rich hair keratin-associated protein in rabbit hair follicles.
22 citations
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July 1998 in “Journal of Investigative Dermatology” This study identified and characterized a gene called 4C32, which is expressed in the periderm of embryonic mouse skin and has a structure similar to keratin-associated proteins.
27 citations
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June 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified numerous size polymorphisms in the human ultrahigh sulfur KAP4 genes due to intragenic sequence variations, suggesting these polymorphisms may have arisen through deletions and duplications during evolution.