41 citations
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March 2017 in “PLoS neglected tropical diseases” This study found that isotretinoin, a drug commonly used for acne, inhibits polyamine transport in Trypanosoma cruzi, leading to trypanocidal effects, and suggests its potential as a treatment for Chagas disease without affecting mammalian cell viability.
41 citations
,
January 2014 in “Annals of Dermatology” This study found that dermoscopy showed distinctive patterns for different types of alopecia, supporting its clinical usefulness for diagnosing diseases with small round or oval hairless patches on the scalp.
38 citations
,
September 2017 in “Oncologist” This source reports that scalp cooling is currently the only safe and FDA-cleared method to potentially reduce chemotherapy-induced hair loss, with about a 50% chance of maintaining sufficient hair to avoid needing a wig.
25 citations
,
April 2018 in “Electromagnetic biology and medicine” This study found that radiofrequency radiation from mobile phone use may increase DNA damage in hair follicle cells of the ear canal, with greater exposure duration linked to higher damage levels.
24 citations
,
March 1998 in “Mycoses” In this study, 31 children with kerion Celsi were treated successfully with antifungal medications, emphasizing the importance of early diagnosis and treatment to prevent scarring and hair loss.
23 citations
,
March 2001 in “Clinics in Dermatology” This article reviews treatment options for male androgenetic alopecia, including minoxidil, 5 alpha reductase inhibitors, and hair transplantation, but reports no new clinical findings.
21 citations
,
September 2001 in “Graefes Archive for Clinical and Experimental Ophthalmology” This study found that minoxidil inhibited lens epithelial cell migration, proliferation, and collagen secretion in vitro, suggesting it may help prevent postoperative capsular opacification.
18 citations
,
January 2000 in “Food Science and Technology Research” In this study, partially purified apple polyphenols were found to inhibit preadipocyte differentiation in mouse cells by reducing GPDH activity and triglyceride accumulation.
16 citations
,
January 2001 in “Clinical and Experimental Dermatology” Photodynamic therapy was effective in treating multiple scalp basal cell carcinomas with minimal side effects and good cosmetic results.
16 citations
,
January 1986 in “Dermatology” In this study, 1% minoxidil lotion led to good results in 18% of male patients with androgenetic alopecia, but only 6% maintained regrowth one year after stopping treatment.
13 citations
,
February 2010 in “Stem Cell Reviews and Reports” Stem cells compete for space using cell adhesion, and mutations can affect their competitive success, with implications for tissue health and disease.
10 citations
,
December 2021 in “Frontiers in cell and developmental biology” This study found that GPC1 is a crucial regulator of angiogenesis in human dermal microvascular endothelial cells, indicating its potential as a target for treating alopecia.
10 citations
,
January 2007 in “Dermatologic Surgery” This study reported that a new surgical technique resulted in minimal scars visible to the naked eye in most cases, suggesting a significant improvement over conventional closure techniques.
8 citations
,
January 2012 in “Dermatology” This paper reports two cases of telogen effluvium in children following HPV vaccination, resolving spontaneously but associated with social and emotional distress.
7 citations
,
August 2019 in “Clinical and Experimental Dermatology” This article is a correspondence discussing the possibility of the Mona Lisa exhibiting frontal fibrosing alopecia instead of Renaissance fashion, but it reports no new clinical findings.
7 citations
,
December 2015 in “Journal of thermal biology” This study used numerical models to explore the cooling power required by different scalp cooling devices to prevent chemotherapy-induced hair loss, finding that coolant temperature significantly influences scalp tissue temperatures.
7 citations
,
December 2004 in “Medicine” This article reviews the anatomy and pathology of skin and hair to aid in diagnosing skin diseases and discusses potential therapies, without reporting new clinical results.
7 citations
,
February 2004 in “Canadian Journal of Anesthesia/Journal canadien d anesthésie” Pressure from surgical headrests can cause temporary hair loss in liver donors.
7 citations
,
November 2001 in “Journal of Vascular Surgery” This address discusses the evolution of surgical training, emphasizing the need for Vascular Surgery to have an independent board to adjust training requirements and improve specialty education without reporting new research findings.
6 citations
,
March 2018 in “Journal of Chromatography A” This study describes an analytical technique combining field-enhanced sample stacking with dispersive liquid-liquid microextraction, offering improved sensitivity for detecting finasteride and its metabolite in urine samples from patients treated for androgenetic alopecia.
5 citations
,
May 2021 in “Veterinary medicine and science” In this study, cosyntropin-induced cortisol spikes did not affect hair cortisol concentration in captive grizzly bears, contrasting with stress responses observed in free-ranging bears during capture.
5 citations
,
April 2017 in “Dermatologic Surgery” PRP treatment satisfies 58% of female hair loss patients, with most noticing fuller, thicker hair and less shedding.
4 citations
,
May 2024 in “Supportive Care in Cancer” In this survey study, participants from scalp cooling Facebook groups reported benefiting from shared experiences, instructions, insurance advice, and product recommendations, although only a minority sought dermatologist consultations, suggesting these groups provide a significant informational platform for chemotherapy-induced alopecia patients.
3 citations
,
January 2019 in “Advances in stem cells and their niches” This review discusses the role of dermal papilla cells in hair follicle morphogenesis and regeneration and reports no new results; the authors emphasize the importance of these cells in hair growth and pigmentation regulation.
2 citations
,
March 2024 in “Supportive Care in Cancer” In this study, manual cold capping was found to be effective in minimizing chemotherapy-induced alopecia, with 92.1% of patients retaining 50% or more of their hair, although effectiveness varied with different chemotherapy regimens.
2 citations
,
January 2004 in “Medical Hypotheses” This hypothesis proposes that fungal infection may be a common risk factor for both male pattern baldness and coronary heart disease, supported by some evidence linking antifungal treatment to improvements in both conditions.
1 citations
,
January 2023 in “Skin appendage disorders” This article discusses the potential association between the use of hair oils and the exacerbation of seborrheic dermatitis in black patients, suggesting more research is needed to understand their impact.
1 citations
,
April 2022 in “Rheumatology” This case study describes a 4-year-old boy with juvenile dermatomyositis whose severe subcutaneous edema resisted conventional treatment, necessitating aggressive immunosuppression for disease control.
1 citations
,
January 2022 in “Electronic Imaging” This study introduces a novel method for digitizing hair color that accurately captures and renders the color appearance of physical hair samples in synthetic images.
1 citations
,
November 2020 in “Journal of The American Academy of Dermatology” This study found that oral spironolactone is generally well tolerated and may be effective for treating female-pattern hair loss, with improvements in hair regrowth stability as measured by Sinclair scores.