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    Glossary Cannabinoid Receptor Type 2

    protein involved in immune response and inflammation regulation

    Cannabinoid Receptor Type 2 (CB2 receptor) is a protein found primarily in the immune system and peripheral tissues. It plays a crucial role in modulating inflammation and immune responses. Unlike its counterpart, the CB1 receptor, which is mainly located in the brain and central nervous system, CB2 receptors are less associated with psychoactive effects and are being studied for their potential therapeutic benefits in conditions like chronic pain, autoimmune diseases, and even hair growth disorders.

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    Research 30 of 276

    1. 438 Laminin-511 is a new player in the development of psoriasis and controlled via cannabinoid receptor type 1 2016
    2. 1370 17β-estradiol may control human HF growth also via up-regulating the expression of cannabinoid receptor type1 expression 2018
    3. 1348 Involvement of mast cells and CB1 in the pathogenesis of IgA vasculitis Journal of Investigative Dermatology · 2023
    4. Peer Review #2 of "A novel control of human keratin expression: cannabinoid receptor 1-mediated signaling down-regulates the expression of keratins K6 and K16 in human keratinocytes in vitro and in situ (v0.1)" 2013
    5. Topical and nutricosmetic products for healthy hair and dermal antiaging using “dual‐acting” (2 for 1) plant‐based peptides, hormones, and cannabinoids FASEB bioAdvances · 2021 · 13 citations
    6. Cannabinoids and Their Receptors in Skin Diseases International journal of molecular sciences · 2023 · 1 citations
    7. Stem Cells and their Niches Journal of Investigative Dermatology · 2013 · 1 citations
    8. Peer Review #1 of "A novel control of human keratin expression: cannabinoid receptor 1-mediated signaling down-regulates the expression of keratins K6 and K16 in human keratinocytes in vitro and in situ (v0.1)" 2013
    9. Cannabinoid Compounds as a Pharmacotherapeutic Option for the Treatment of Non-Cancer Skin Diseases Cells · 2022 · 3 citations
    10. Effect of Hataedock Treatment on Epidermal Structure Maintenance through Intervention in the Endocannabinoid System Evidence-based Complementary and Alternative Medicine · 2020 · 2 citations
    11. Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C(ut)annabinoid” System 2019 · 142 citations
    12. A novel control of human keratin expression: cannabinoid receptor 1-mediated signaling down-regulates the expression of keratins K6 and K16 in human keratinocytes<i>in vitro</i>and<i>in situ</i> PeerJ · 2013 · 66 citations
    13. Targeting Cutaneous Cannabinoid Signaling in Inflammation - A “High”-way to Heal? EBioMedicine · 2017 · 28 citations
    14. Endocannabinoids limit excessive mast cell maturation and activation in human skin Journal of Allergy and Clinical Immunology · 2012 · 124 citations
    15. Frontal fibrosing alopecia: A review of disease pathogenesis Frontiers in Medicine · 2022 · 2 citations
    16. The impact of cannabis use on local anesthetic dosing during hair restoration surgery: a case report, proposed mechanisms, and clinical recommendations Journal of Dermatological Treatment · 2025
    17. 1317 Nicotinic acid suppresses sebaceous lipid synthesis of human sebocytes via activating hydroxycarboxylic acid receptor 2 (HCA2) Journal of Investigative Dermatology · 2018
    18. Neuroendocrine Controls of Keratin Expression in Human Skin IntechOpen eBooks · 2018
    19. Mechanisms of Disease: selective inhibition of 11β-hydroxysteroid dehydrogenase type 1 as a novel treatment for the metabolic syndrome Nature Clinical Practice Endocrinology & Metabolism · 2005 · 69 citations
    20. Angelica gigas Nakai (Korean Dang-gui) Root Alcoholic Extracts in Health Promotion and Disease Therapy – active Phytochemicals and In Vivo Molecular Targets Pharmaceutical Research · 2025 · 2 citations
    21. Beyond acne: Current aspects of sebaceous gland biology and function Reviews in Endocrine and Metabolic Disorders · 2016 · 97 citations
    22. Getting under the skin of hair aging: the impact of the hair follicle environment Experimental Dermatology · 2020 · 20 citations
    23. The Effect of Parathyroid Hormones on Hair Follicle Physiology: Implications for Treatment of Chemotherapy-Induced Alopecia Skin Pharmacology and Physiology · 2015 · 15 citations
    24. Neurosteroidogenesis Today: Novel Targets for Neuroactive Steroid Synthesis and Action and Their Relevance for Translational Research Journal of Neuroendocrinology · 2015 · 123 citations
    25. Novel 5α-Reductase Inhibitors:  Synthesis, Structure−Activity Studies, and Pharmacokinetic Profile of Phenoxybenzoylphenyl Acetic Acids Journal of Medicinal Chemistry · 2005 · 18 citations
    26. Poster Abstracts Fundamental & Clinical Pharmacology · 2017
    27. Unravelling a novel role for cannabidivarin in the modulation of subventricular zone postnatal neurogenesis European Journal of Pharmacology · 2023 · 7 citations
    28. Treatment Advances for Acne Vulgaris: The Scientific Role of Cannabinoids Cosmetics · 2024 · 1 citations
    29. GPCRs as key regulators in wound healing Frontiers in Cell and Developmental Biology · 2026
    30. Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D2 Synthase as a Multifunctional Lipocalin Frontiers in Physiology · 2021 · 18 citations