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Glossary Cannabigerol

non-psychoactive cannabis compound, precursor to other cannabinoids

Cannabigerol (CBG) is a non-psychoactive cannabinoid found in the cannabis plant. It is often referred to as the "mother of all cannabinoids" because it is the precursor from which other cannabinoids, such as THC and CBD, are synthesized. CBG is being studied for its potential therapeutic benefits, including anti-inflammatory, antibacterial, and neuroprotective properties.

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research Potential Medical Uses of Cannabigerol: A Brief Overview

14 citations , January 2017 in “Elsevier eBooks”

This review explores cannabigerol (CBG) as a potential therapeutic agent with various pharmacological activities but reports no new clinical results, emphasizing the need for further research on its efficacy and safety.

research The Role of Cannabinoids in the Treatment of Skin Diseases: A Review of Mechanisms of Action and Clinical Evidence

1 citations , November 2025 in “Journal of Education Health and Sport”

This study suggests that cannabinoids, especially CBD, show promise as potential treatments for various inflammatory, infectious, and autoimmune skin diseases, with ongoing research needed to confirm clinical efficacy and safety.

research Scientific Evidence for the Cosmetic Skin and Hair Benefits of Hemp-derived Cannabinoids: A Review

January 2024 in “Clinical dermatology open access journal”

This paper reviews existing research on the cosmetic benefits of hemp-derived cannabinoids for skin and hair, highlighting their unique mechanisms of action, while discussing formulation, legal, and regulatory challenges associated with using these compounds in cosmetic products.

research 263 (-)-cannabidiol differentially influences hair growth

3 citations , September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study found that low concentrations of CBD promoted hair follicle growth, while higher concentrations induced hair follicle regression and increased cell death in an experimental setting.

research A cannabinoid Hairy‐Tale: Hair loss or hair gain?

2 citations , October 2022 in “Journal of cosmetic dermatology”

This study observed that a CBD-rich topical cannabis extract may increase hair count in patients with androgenetic alopecia when applied daily, but the effect is concentration-dependent and requires further research to establish safety and efficacy.

research Phytochemical study of Bituminaria basaltica aerial parts, an Italian endemism

5 citations , March 2017 in “Natural Product Research”

This study identified and characterized eight compounds, including furanocoumarins and pterocarpans, from the aerial parts of Bituminaria basaltica, with β-caryophyllene and germacrene D as main constituents of its essential oil.

research A Summary of Pre-Clinical and Clinical Evidence for Cannabinoid Hair Follicle Effects

January 2022 in “Clinical dermatology open access journal”

This review summarizes research on cannabinoids like CBD and THCV, reporting that they improve hair growth in patients with androgenetic alopecia when applied topically, with CBD showing a dose-dependent effect.

research Cannabinoids: Current and Future Options to Treat Chronic and Chemotherapy-Induced Neuropathic Pain

50 citations , May 2019 in “Drugs”

This review discusses the potential therapeutic effects of targeting the endocannabinoid system for chemotherapy-induced peripheral neuropathy and reports no new clinical results, highlighting the need for ongoing research.

research How drug repurposing can advance drug discovery: challenges and opportunities

33 citations , August 2024 in “Frontiers in Drug Discovery”

In this article, the authors describe how drug repurposing, supported by large-scale data and artificial intelligence, can make drug discovery more cost-effective and expedient compared to traditional methods, despite certain regulatory challenges.

Sebaceous Immunobiology: Skin Homeostasis, Innate Immunity Coordination, Inflammatory Response, and Disease Associations

research Sebaceous immunobiology - skin homeostasis, pathophysiology, coordination of innate immunity and inflammatory response and disease associations

21 citations , November 2022 in “Frontiers in immunology”

This article reviews sebaceous immunobiology and highlights the complex role of sebaceous glands and sebocytes in skin barrier function and inflammation, particularly in acne pathogenesis, but reports no new results.

research The role of hemp (Cannabis sativa L.) in cosmeceuticals and personal care: A systematic review

November 2025 in “International Journal of Applied and Experimental Biology”

In this review, the authors discussed the potential of hemp in cosmeceutics for skin conditions like acne and dermatitis, emphasizing its therapeutic properties and formulation challenges but noting the need for standardizing cannabinoid content and documenting effectiveness.

research Case Study of Hair Regrowth with Topical Cannabidiol (CBD)

1 citations , July 2021 in “Hair transplant forum international”

This study found a 93.5% increase in nonvellus hair after 6 months of daily topical CBD application on the scalp in individuals with androgenetic alopecia, with no reported adverse effects.

research Cinnamomi Cortex (Cinnamomum verum) Suppresses Testosterone-induced Benign Prostatic Hyperplasia by Regulating 5α-reductase

43 citations , August 2016 in “Scientific Reports”

This animal study found that Cinnamomi cortex water extract reduced prostate weight and improved histological changes in a benign prostatic hyperplasia model, suggesting potential as a treatment.

research 477 How Cannabidiol Supports Hair Growth: From Epigenetics to the Scalp Microbiome

November 2025 in “Journal of Investigative Dermatology”

CBD can help hair grow by supporting scalp health and reducing inflammation.

research Germacrene Analogs are Anti-androgenic on Androgen-dependent Cells

3 citations , September 2016 in “Natural Product Communications”

This study identified 8-hydroxy germacrene B from Curcuma aeruginosa as a highly potent in-vitro 5-alpha reductase inhibitor with significant anti-androgenic activity, while exhibiting mild cytotoxicity on prostate cancer cells without affecting human dermal papilla cells at tested concentrations.

research Unravelling a novel role for cannabidivarin in the modulation of subventricular zone postnatal neurogenesis

7 citations , October 2023 in “European Journal of Pharmacology”

This study found that Cannabidivarin (CBDV) promotes neuronal differentiation and inhibits oligodendrocyte maturation via TRPV1 modulation, highlighting its potential in neural stem cell research.

The Phytocannabinoid (–)-Cannabidiol Operates as a Complex, Differential Modulator of Human Hair Growth: Anti-Inflammatory Submicromolar Versus Hair Growth Inhibitory Micromolar Effects

research The Phytocannabinoid (–)-Cannabidiol Operates as a Complex, Differential Modulator of Human Hair Growth: Anti-Inflammatory Submicromolar versus Hair Growth Inhibitory Micromolar Effects

15 citations , July 2019 in “Journal of Investigative Dermatology”

This exploratory study found that cannabidiol (CBD) at higher concentrations may inhibit hair growth by promoting the onset of catagen in human hair follicles, while lower concentrations showed potential anti-inflammatory effects without promoting catagen.

research Beta-caryophyllene enhances wound healing through multiple routes

3 citations , April 2019 in “bioRxiv (Cold Spring Harbor Laboratory)”

In this study, beta-caryophyllene enhanced wound healing in female mice by improving re-epithelialization, cell proliferation, and cell migration, suggesting potential benefits of essential oil compounds in inflammation reduction.

research Immunomodulatory Potential of a Bibenzyl-dihydrophenanthrene Derivative Isolated from Calanthe cardioglossa

3 citations , January 2025 in “Journal of Natural Products”

In this study, researchers isolated new compounds from the plant *Calanthe cardioglossa* and found that five of these compounds, particularly calancardin B, significantly reduced TNF-α levels in immune cells relevant to multiple sclerosis, suggesting potential for immunomodulatory effects.

research Skin applications of cannabidiol: sources, effects, delivery systems, marketed formulations and safety

1 citations , March 2023 in “Phytochemistry Reviews”

This review discusses the potential of CBD for treating skin disorders, the challenges of its topical administration, and current strategies to improve its application, but reports no new clinical findings.

Amelioration of Symptoms of Dry and Eczema-Prone Skin by an Oil-in-Water Emulsion Containing a Combination of Zingiber Officinale Root Extract and CBD with Antioxidative and Anti-Inflammatory Activity In Vitro

research 599 Amelioration of symptoms of dry and eczema-prone skin by an oil-in-water emulsion containing a combination of a zingiber officinale root extract and cbd with antioxidative and anti-inflammatory activity in vitro

April 2023 in “Journal of Investigative Dermatology”

In this study, a new emulsion containing CBD and ginger root extract significantly reduced symptoms of dry and eczema-prone skin, such as erythema and itching, in a clinical trial.

research Unravelling a novel role for Cannabidivarin in the modulation of subventricular zone postnatal neurogenesis

May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

This study found that Cannabidivarin (CBDV) promotes neuronal survival, proliferation, and differentiation via TRPV1 activation but inhibits oligodendrocyte differentiation in postnatal neurogenesis.

research Anti-androgenic effect of sesquiterpenes isolated from the rhizomes of Curcuma aeruginosa Roxb.

44 citations , March 2012 in “Fitoterapia”

In this study, germacrone from Curcuma aeruginosa showed anti-androgenic effects by inhibiting 5α-reductase, suggesting its potential as a lead compound for treating androgen-dependent disorders.

research HPLC-ESI-MSn characterization of phenolic compounds, terpenoid saponins, and other minor compounds in Bituminaria bituminosa

76 citations , February 2015 in “Industrial Crops and Products”

This study identified over 40 phytochemical compounds in the leaves and flowers of Bituminaria bituminosa, predominantly glycosylated flavonoids from apigenin, using advanced chromatographic techniques.

research Hair Regrowth with Cannabidiol (CBD)-rich Hemp Extract – A Case Series

7 citations , April 2021 in “Cannabis”

In this study, topical CBD significantly increased hair count by 93.5% over six months in individuals with androgenetic alopecia, with no adverse effects reported.

research Beta-caryophyllene enhances wound healing through multiple routes

67 citations , December 2019 in “PloS one”

This study found that beta-caryophyllene enhanced re-epithelialization in cutaneous wounds of female mice, suggesting its potential for improving wound healing through multiple pathways.

research Chemical profiles and pharmacological attributes of Apis cerana indica beehives using combined experimental and computer-aided studies

15 citations , March 2023 in “Heliyon”

This study found that water-soluble beehive extract exhibited anxiolytic, antidepressant, and anti-inflammatory effects in animal models.

research Cannabinoids for skin diseases and hair regrowth

20 citations , August 2021 in “Journal of Cosmetic Dermatology”

This review examines the potential use and challenges of topical cannabinoids for skin diseases and hair growth, highlighting limited clinical data on their efficacy and safety.

Gas Chromatography Coupled to Mass Spectrometry Characterization, Anti-Inflammatory Effect, Wound-Healing Potential, and Hair Growth-Promoting Activity of Algerian Carthamus Caeruleus L (Asteraceae)

research Gas chromatography coupled to mass spectrometry characterization, anti-inflammatory effect, wound-healing potential, and hair growth-promoting activity of Algerian Carthamus caeruleus L (Asteraceae)

7 citations , May 2018 in “Indian Journal of Pharmacology”

This study found that the methanolic extract of Carthamus caeruleus roots significantly reduced inflammation, promoted wound healing, and enhanced hair growth in experimental models, supporting its traditional use in Northern Algeria as a skincare remedy.

research Phytochemical study, quality control and development of a phytotherapeutic formulation of Copaifera officinalis (copaiba) resin oil for adjuvant therapy of cancer patients.

July 2023 in “LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)”

This study evaluated the resin oil of Copaifera officinalis L., identifying 64 compounds and developing validated analytical methods for quality control, and formulated a stable pharmaceutical foam, laying groundwork for potential clinical applications of copaiba oil.