research Single-Cell Transcriptomics Reveals a Senescence-Associated IL-6/CCR6 Axis Driving Radiodermatitis
Blocking certain immune signals can reduce skin damage from radiation therapy.
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research Expression and Functional Relevance of Melatonin Receptors in Hair Follicle Biology
Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.
research Activity of Sorafenib Against Desmoid Tumor/Deep Fibromatosis
Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.
research Melatonin: A Cutaneous Perspective on Its Production, Metabolism, and Functions
Melatonin may benefit skin health and could be a promising treatment in dermatology.
research Epithelial-To-Mesenchymal Transition in Cutaneous Wound Healing: Where We Are and Where We Are Heading
The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.
research Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts During Wound Healing
Dermal fibroblasts have adjustable roles in wound healing, with specific cells promoting regeneration or scar formation.
research Roles of the Hedgehog Signaling Pathway in Epidermal and Hair Follicle Development, Homeostasis, and Cancer
The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.
research Epidermal Stem Cells: Practical Perspectives and Potential Uses
Epidermal stem cells could lead to new treatments for skin and hair disorders.
research The Non-Neuronal and Nonmuscular Effects of Botulinum Toxin: An Opportunity for a Deadly Molecule to Treat Disease in the Skin and Beyond
Botulinum toxin has potential for treating various skin conditions and improving wound healing.
research Eph/Ephrin Signaling in Epidermal Differentiation and Disease
Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
research Azasteroids as Inhibitors of Testosterone 5α-Reductase in Mammalian Skin
Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.
research Intermittent Treatment with Farnesyltransferase Inhibitor and Sulforaphane Improves Cellular Homeostasis in Hutchinson-Gilford Progeria Fibroblasts
Alternating treatment with two drugs could help cells in a rapid aging disease.
research Fibromodulin Deficiency Alters Temporospatial Expression Patterns of Transforming Growth Factor-β Ligands and Receptors During Adult Mouse Skin Wound Healing
Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.
research Inhibition of the Androgen Receptor by Antisense Oligonucleotides Regulates the Biological Activity of Androgens in SZ95 Sebocytes
Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.
research Expression and Function of Nuclear Receptor Co-Activator 4: Evidence of a Potential Role Independent of Co-Activator Activity
NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.
research 3,4,5-Tri-O-Caffeoylquinic Acid Promoted Hair Pigmentation Through β-Catenin and Its Target Genes
A substance called TCQA could potentially darken hair by activating certain genes and increasing melanin.
research Analysis of Changes in MicroRNA Expression Profiles in Response to the Troxerutin-Mediated Antioxidant Effect in Human Dermal Papilla Cells
Troxerutin helps protect skin cells from oxidative stress and may be good for treating hair loss.
research Complex Changes in the Apoptotic and Cell Differentiation Programs During Initiation of the Hair Follicle Response to Chemotherapy
Chemotherapy causes complex changes in hair follicle cells that can lead to hair loss.
research Challenges Associated With the Identification of Germline Variants on Myeloid Malignancy Genomic Profiling—A Singaporean Experience
Genomic profiling for myeloid cancers can find important inherited mutations, but it's challenging when these mutations aren't related to the patient's symptoms.
research Fluoroscopy-Induced Morphea
A man developed a painful skin condition after multiple heart procedures involving radiation.
research Distinct Stem Cells Contribute to Mammary Gland Development and Maintenance
Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.
research Melatonin Membrane Receptors in Peripheral Tissues: Distribution and Functions
Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.
research Modulating the Stem Cell Niche for Tissue Regeneration
Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.
research Molecular Principles of Hair Follicle Induction and Morphogenesis
Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.
research Sexual Hormones in Human Skin
Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.
research Cell Death in the Skin: Mechanisms and Implications
Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
research The Roles of Wnt/β-Catenin Pathway in Tissue Development and Regenerative Medicine
The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.
research The Peripheral Clock Regulates Human Pigmentation
Certain genes control the color of human hair by affecting pigment production.
research Alteration of Skin Properties with Autologous Dermal Fibroblasts
Using your own skin cells can help repair aging skin and promote hair growth.
research Skin Keratins
Keratins are important for skin cell health and their problems can cause diseases.