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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Sulforaphane from broccoli can help protect skin from sun damage.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Certain drugs that block specific enzymes can help treat prostate diseases.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

The U.S. military's teledermatology program was effective in providing fast and successful skin care in remote locations, preventing unnecessary evacuations.

Hormone therapies like birth control pills and spironolactone are safe and effective for treating women's adult acne.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Infertile men are more likely to produce sperm with abnormal chromosome numbers, which can affect pregnancy success and embryo health.

Baricitinib for severe alopecia areata is generally safe, with common side effects like infections and acne, and low rates of serious complications.

A mouse gene mutation increases the risk of skin cancer.

The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.

DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.

Adding cerium(III) chloride to Grignard reagents improves the making of compounds that could treat prostate issues and hair loss.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

A new gel form of minoxidil is equally effective for hair growth and safer for the heart and other organs than the traditional solution.

Invasomes effectively deliver drugs through the skin and have potential for improved treatments.

Certain skin cells near the base of hair muscles may help renew and stabilize skin, possibly affecting skin disorder understanding.

Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.

A new, efficient method has been developed to detect darolutamide and thalidomide, drugs used for certain hair loss and prostate cancer treatments, in pharmaceuticals and body fluids.

A man with a rare scalp cancer was successfully treated, highlighting the need for early management to prevent spread and complications.

Skin cancer often starts from Lgr5+ progenitor cells.

Connarus semidecandrus Jack extract promotes hair growth and thickness, reduces prostate cancer cell growth, and could potentially be used as a treatment for hair loss.

The main prostate diseases in dogs are benign growth, infections, and cancer, with various treatments ranging from drugs to surgery, but cancer treatments have limited success.

Most pediatric cancer patients at Muhimbili National Hospital in Tanzania experienced side effects from chemotherapy, with nausea, hair loss, and low white blood cell count being the most common.

Infrared radiation can cause skin aging and cancer at high temperatures but may have therapeutic benefits at controlled levels.

Azelaic acid treats acne, rosacea, and hyperpigmentation with minimal side effects.