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Brg1 is crucial for keeping hair follicle stem cells and repairing skin, working with the Sonic Hedgehog pathway to promote hair growth.

Finasteride and dutasteride might lower melanoma risk.

The 2003 consensus updated PCOS diagnosis criteria and highlighted increased risks of diabetes and heart disease for those affected.

Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Sulforaphane from broccoli can help protect skin from sun damage.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Skin side effects from cancer drugs targeting EGFR can affect treatment adherence but can be managed with antibiotics like tetracycline.

GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.

Vitamin D and its receptor may help prevent skin cancer.

UVB radiation harms hair growth and health, causing cell death and other changes in human hair follicles.

Researchers created rat liver stem cells that could help repair liver failure in rats and may be useful for studying human liver diseases.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.

Researchers isolated a new type of stem cell from mouse skin that can renew itself and turn into multiple cell types.

Human placenta hydrogel helps restore cells needed for hair growth.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

The 3D scaffold helped maintain hair cell traits and could improve hair loss treatments.