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Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.

Overexpressing SSAT enzyme reduces prostate tumor growth in mice.

Hedgehog pathway inhibitors can treat certain aggressive cancers but face limitations like resistance and side effects.

The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.

Natural small molecules can help treat diseases by activating or inhibiting the Wnt pathway.

Human dental pulp stem cell-conditioned medium, especially from hypoxic conditions, may help treat chemotherapy-induced hair loss and does not increase cancer risk.

Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.

Polyamines help fix DNA damage accurately in cells.

Adding a specific gene to skin cells can help treat skin disorders like psoriasis.

Melanoblasts migrate to the skin using various pathways, and understanding this process could help with skin disease research.

MPA increases cancer spread by boosting Eph A2 activity.

This enzyme helps metabolize fatty acids and isoleucine, and could be key in treating neurological diseases and certain cancers.

4-octyl itaconate may prevent hearing loss caused by the drug cisplatin by activating certain cell protection pathways.

Some supplements may help reduce side effects of cancer treatments in pets.

Overexpression of HDGF in melanocytes does not cause cancer.

GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.

The fish oil-based gel with imiquimod improves skin cancer treatment and reduces inflammation.

AHCC reduces hair loss and liver injury caused by chemotherapy in rodents.

Saw palmetto extract may help treat brain tumors by blocking a specific growth signal and blood vessel formation.

Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.

Wnt signaling is crucial for skin development and hair growth.

The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

ERG increases SOX9, promoting prostate cancer growth and invasion.

Hair follicle cells resist turning into skin cells.

Chemotherapy drugs can cause abnormal growth and changes in healthy skin and gland cells.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

The reviewers suggest clarifying the abstract, adding background on inflammation's effect on stem cells and cancer, discussing immune cells' role in tumors, and considering inflammation's potential to reduce cancer growth.

Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.

ATP-sensitive K+ channel subunits, particularly Sur2A, play a significant role in various cancers.