research Logic-Based Modeling and Drug Repurposing for the Prediction of Novel Therapeutic Targets and Combination Regimens Against E2F1-Driven Melanoma Progression
Tadalafil and Finasteride may help treat aggressive melanoma.
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research Antiviral Drugs Prolong Survival in Murine Recessive Dystrophic Epidermolysis Bullosa
Antiviral drugs, especially daclatasvir, may be a new treatment for a rare skin disease, improving survival and reducing symptoms in mice.
research Sostdc1 Defines the Size and Number of Skin Appendage Placodes
Sostdc1 controls the size and number of hair and mammary gland structures.
research Perilla Frutescens: A Rich Source of Pharmacologically Active Compounds
Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.
research Flavonoids and Saponins: What Have We Got or Missed?
More high-quality research is needed to recommend flavonoids and saponins for clinical use.
research Off-Label Uses of Retinoids in Dermatology
Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.
research The Role of Heat Shock Proteins in the Pathogenesis of Polycystic Ovarian Syndrome: A Review of the Literature
Heat Shock Proteins are important in the development of Polycystic Ovarian Syndrome and could be targets for new treatments.
research A Guide to the Use of Bioassays in Exploration of Natural Resources
Bioassays help find useful compounds in nature for making medicines, supplements, and cosmetics.
research Hormonal and Genetic Etiology of Male Androgenetic Alopecia
research Enzymes
Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.
research The Potential Application of Nanocarriers in Delivering Topical Antioxidants
Nanocarriers can improve antioxidant delivery to the skin but face safety and production challenges.
research Male Androgenetic Alopecia
Male pattern baldness worsens with age and can be treated with medications like minoxidil and finasteride, but side effects and personalized care are important.
research Role of FGFR2-Signaling in the Pathogenesis of Acne
Increased FGFR2b signaling, influenced by androgens, plays a role in causing acne.
research Pharmacological Efficacy of Tamarix Aphylla: A Comprehensive Review
Tamarix aphylla may be effective for various medical conditions, but more research is needed to confirm its safety and effectiveness.
research Supraphysiological Dose of Testosterone Impairs the Expression and Distribution of Sex Steroid Receptors During Endometrial Receptivity Development in Female Sprague-Dawley Rats
High doses of testosterone disrupt hormone levels and receptor expression in the uterus, affecting fertility.
research Skin Deep and Deeper: Multiple Pathways in Basal Cell Carcinogenesis
The research suggests new treatments for skin cancer could target specific cell growth pathways.
research Signaling Involved in Hair Follicle Morphogenesis and Development
The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.
research Clinical Management of Cutaneous Adverse Events in Patients on Targeted Anticancer Therapies and Immunotherapies: A National Consensus Statement by the Spanish Academy of Dermatology and Venereology and the Spanish Society of Medical Oncology
Spanish experts provided guidelines for treating skin side effects in cancer patients on new therapies, stressing early action and teamwork.
research The Role of Dexamethasone in Mediating the Contradictory Effects of Wnt Antagonists SFRP2 and SFRP3 on Human Hair Follicle Growth
Dexamethasone affects hair growth by altering levels of proteins that either promote or inhibit hair follicle growth.
research The Inhibitory Effect of Scutellaria Baicalensis Extract and Its Active Compound, Baicalin, on the Translocation of the Androgen Receptor with Implications for Preventing Androgenetic Alopecia
Scutellaria baicalensis extract and baicalin may help prevent hair loss.
research Expression Patterns of Gli-1, Pleckstrin Homology-Like Domain, Family A, Member 1, Transforming Growth Factor-β1/β2, and p63 in Sebaceous and Follicular Tumors
The research suggests that p63 and TGF-β1 may help determine tumor type and malignancy in hair follicle and sebaceous tumors.
research Patched-Associated Tumors: Modifier Genes and Pathogenesis
The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.
research Stem Cells in the Skin
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
research Regulation of Stem Cell Fate by HSPGs: Implication in Hair Follicle Cycling
HSPGs help control stem cell behavior, affecting hair growth and offering a target for hair loss treatments.
research Beta Human Papillomavirus and Merkel Cell Polyomavirus in Skin Neoplasms
Beta-HPV and MCPyV are linked to certain skin cancers, with ongoing research and vaccine development.
research Cell Therapy for Androgenetic Alopecia: Elixir or Trick?
Stem cell therapies could be a promising alternative for hair loss treatment, but more research is needed to understand their full potential and safety.
research Blue Light in Dermatology
Blue light can help treat skin conditions like eczema and acne without major side effects.
research Rosmarinus Officinalis Essential Oil Increases Hair Length and Follicle Diameter of Ultraviolet B-Exposed Mice Through VEGF
Rosemary essential oil improved hair growth and thickness in UVB-exposed mice.
research The Roles of Non-Coding RNA in the Development and Regeneration of Hair Follicles: Current Status and Further Perspectives
Non-coding RNAs are important for hair growth and could lead to new hair loss treatments, but more research is needed.
research Acne
Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.