32 citations
,
January 2000 in “International Journal of Cancer” In this study, the researchers observed significant down-regulation of Transglutaminase-3 expression in esophageal cancer tissues compared to normal tissues, suggesting its alteration is a common event in esophageal cancer development.
31 citations
,
August 2022 in “Frontiers in Oncology” This review discusses the potential benefits of photobiomodulation for managing side effects of cancer therapy and provides specific guidelines for its use in supportive cancer care, without presenting new clinical results.
29 citations
,
February 2021 in “Cancers” This review discusses the role of ion channels in ovarian cancer progression and chemotherapy resistance, highlighting their potential as targets for diagnosis and treatment, but reports no new clinical results.
29 citations
,
March 2010 in “Cancer epidemiology” This study found that early-onset male pattern baldness was associated with a reduced relative risk of prostate cancer.
28 citations
,
May 2012 in “Veterinary Dermatology” In this study, dogs with hair cycle disorders, especially those with alopecia X, showed a significant increase in the number of kenogen follicles, suggesting impaired induction of new hair growth phases.
28 citations
,
January 2017 in “EBioMedicine” This study discusses potential anti-inflammatory roles of endocannabinoid system modulation and phytocannabinoids in skin health, but reports no new clinical results; the authors emphasize the need for further clinical exploration.
28 citations
,
August 2014 in “Cancer Causes & Control” In this study, there was no evidence that using 5α-reductase inhibitors for either short or long durations increased the risk of male breast cancer.
27 citations
,
November 2021 in “Scientific Reports” This study used bioinformatics to explore molecular differences in testicular and ovarian responses to SARS-CoV-2, identifying genes that could be associated with sex differences in infection outcomes.
23 citations
,
January 2016 in “Forensic Science International” This study found that in vitro heat straightening of hair reduced THC and cocaine concentrations but increased CBN and BZE levels, suggesting heat conversion of these substances.
21 citations
,
June 2011 in “Investigative Ophthalmology & Visual Science” This article argues that human scalp hair follicles could serve as a surrogate model for studying immune privilege in the human eye, offering a novel approach for ocular IP research.
21 citations
,
March 2013 in “Cancer Epidemiology, Biomarkers & Prevention” This study found that early-onset baldness in African-American men is associated with an increased risk of developing prostate cancer and more aggressive tumors, with potential interactions involving age and smoking.
20 citations
,
March 2021 in “Cancers” This study found that rare germline pathogenic variants in BRCA2, BRCA1, and ATM are associated with increased risk of aggressive prostate cancer.
20 citations
,
November 2013 in “The Open Cancer Journal” This observational study provides cause-specific mortality estimates to help patients and physicians better understand long-term outcomes for localized prostate cancer based on initial treatment choices.
20 citations
,
May 2023 in “Cancer Nanotechnology” The researchers reported that their novel formulation of pterostilbene-loaded ethoniosomes with folic acid coating effectively targeted lung cancer cells in vitro and demonstrated promising results in animal models, indicating potential for future targeted chemotherapy applications.
20 citations
,
August 2021 in “Journal of Cosmetic Dermatology” This review examines the potential use and challenges of topical cannabinoids for skin diseases and hair growth, highlighting limited clinical data on their efficacy and safety.
20 citations
,
January 2013 in “Cell & Bioscience” This review discusses recent findings on the epigenetic regulation of adult stem cells and cancer stem cells, highlighting shared and distinct features, and reports no new clinical results.
17 citations
,
January 2014 in “Stem Cells Translational Medicine” This study reports that epidermal neural crest stem cells from dogs (cEPI-NCSC) can generate neural crest derivatives and may offer a new cell-based therapy for canine spinal cord injury, with potential as a model for human treatments.
17 citations
,
November 2012 in “Cancer Epidemiology, Biomarkers & Prevention” This study observed that men with vertex androgenetic alopecia at age 40 had a higher risk of early-onset prostate cancer, suggesting a potential link between the conditions.
16 citations
,
November 2019 in “Nanomedicine” This study discusses the potential of thermoresponsive nanogels for improving dermal delivery of therapeutics, highlighting their ability to enhance skin penetration and control drug release with minimal damage to the skin's natural barrier.
16 citations
,
February 2018 in “BMC Genomics” This paper reviews genome-based personalized medicine developments using Web services for analyzing SNPs in reproductive potential but reports no new clinical findings.
16 citations
,
August 2015 in “Journal of Experimental & Clinical Cancer Research” This study found that active telethermography could help identify cancerization fields in individuals with actinic keratosis by detecting hyperthermic halos around tumors, which showed significant changes after treatment with a photolyase device.
16 citations
,
February 2014 in “Journal of Investigative Dermatology” This study developed a mouse model to monitor hair follicle cycling macroscopically through live bioluminescence imaging, enabling detailed analysis of hair cycle and propagation dynamics influenced by environmental factors.
16 citations
,
July 2016 in “Veterinary Dermatology” This study found that dermoscopy can identify distinctive features in canine pattern alopecia, such as hair shaft thinning and pigmentation patterns, which may aid in diagnosing this and potentially other skin disorders.
16 citations
,
January 1995 in “Dermatology” This case report discusses chronic mucocutaneous candidiasis with autoimmune and immune deficiencies in candidiasis-endocrinopathy syndrome, noting associated alopecia areata, ineffective topical immunotherapy, and asplenia.
15 citations
,
April 2021 in “International Journal of Pharmaceutics” This study found that smaller mesoporous silica particles (400-600 nm) accumulated in skin furrows, suggesting their potential as carriers for enhancing the delivery of topical medications like metronidazole.
15 citations
,
June 2019 in “Experimental Dermatology” The authors suggest that the neuroendocrine system of the skin represents a promising target for repurposing drugs, such as cannabidiol and fingolimod, as topical treatments for inflammatory skin diseases.
15 citations
,
March 2014 in “Body Image” This paper explores the social challenges individuals with medical hair loss face when using wigs, highlighting the complex identity management involved and the social obligations to disclose wig use to close ones.
15 citations
,
July 2019 in “Journal of Investigative Dermatology” This exploratory study found that cannabidiol (CBD) at higher concentrations may inhibit hair growth by promoting the onset of catagen in human hair follicles, while lower concentrations showed potential anti-inflammatory effects without promoting catagen.
15 citations
,
March 2018 in “Cancer Medicine” This study found that alopecia areata patients had a slightly decreased overall cancer risk, with significantly lower risks for some cancers but higher risks for lymphoma, breast, kidney, and urinary bladder cancers.
15 citations
,
June 1993 in “Archives of Dermatology” This letter discusses the causes of gray hair, noting both genetic factors and potential associations with other conditions or certain medications, but reports no new findings.