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Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

The research provides insights into hair follicle growth in forest musk deer by identifying key genes and pathways involved.

Eurycoma longifolia extract may help increase testosterone levels and reduce andropause symptoms.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Olfactory receptors found outside the nose may offer new treatments for diseases like cancer and help in wound healing and hair growth.

Signaling pathways are crucial for hair growth in goats.

Proteomics combined with other technologies can lead to a better understanding of skin diseases.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Prunus mira kernels contain components that can promote hair growth in mice.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

EGFR and mTOR inhibitors may help manage Olmsted syndrome symptoms.

Many popular skincare products claim to prevent aging but lack strong evidence to prove their effectiveness and safety.

Combining mood stabilizers with antipsychotics is more effective for treating children with bipolar disorder than using mood stabilizers alone.

Stress can worsen skin conditions by affecting hormone levels and immune response.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Pregnenolone might help manage movement issues caused by Parkinson's disease treatment without reducing the medicine's effectiveness.

Syndecan-1 is essential for maintaining skin fat and preventing cold stress.

*Acorus calamus* has many medicinal benefits but needs more safety research.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

Melatonin, the sleep hormone, can help treat skin conditions like dermatitis, hyperpigmentation, and scalp disorders, and may also aid in skin aging prevention and regeneration. However, it's not recommended for asthma due to its pro-inflammatory effect.

Some skin diseases and their treatments can negatively affect male fertility.

The research provides a gene-based framework for hair biology, highlighting the Hippo pathway's importance and suggesting links between hair disorders, cancer pathways, and the immune system.

Different types of sun exposure damage skin cells and immune cells, with chronic exposure leading to more severe and lasting damage.

Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.

Nanoparticles may improve caffeine delivery for hair growth, offering a potential alternative to minoxidil for hair loss treatment.

CD4+ skin cells may be precursors to basal cell carcinoma.

A substance called TCQA could potentially darken hair by activating certain genes and increasing melanin.