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PDGF-BB helps young melanocytes grow but stops mature ones from growing, and it makes melanocytes more specialized.

Removing part of the vitamin D receptor stops vitamin D from working properly.

The ITGB6 gene is important for tissue repair and hair growth, and mutations can lead to enamel defects and other health issues.

The PIP5K1A gene helps cashmere growth in goats by promoting cell proliferation, and melatonin boosts its expression.

Researchers found 15 new genetic links to skin traits in Japanese women.

Tissue-derived extracellular vesicles are crucial for cancer diagnosis, prognosis, and treatment.

Certain genes control the color of human hair by affecting pigment production.

New treatments for Alopecia Areata, like JAK inhibitors, show promise for hair regrowth and are likely to change future treatment approaches.

VEGFR-2 activation is likely involved in hair follicle growth, survival, and development.

Key proteins and pathways regulate wool fiber diameter in Alpine Merino sheep.

Chinese domestic goats have unique genetic traits due to domestication and geographic isolation.

ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Cilostazol helps hair grow by making hair root cells grow faster and changing growth factor levels.

R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.

A patient with Satoyoshi syndrome improved with a treatment combining several medications, including carbamazepine and methotrexate.

Scientists discovered a new way UVB light increases skin pigmentation through the ATP-P2X7 pathway.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Estrogen therapy can reduce skin aging but has cancer risks.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Skin fat helps with body temperature control and has other active roles in health.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Adenosine helps hair grow longer and stronger by boosting certain growth factors and signaling pathways.

Regenerative therapies show promise for treating vitiligo and alopecia areata.