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The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Spironolactone may cause sexual pain and arousal issues in women, which can improve after stopping the drug and using hormone cream.

Medicines for enlarged prostate may raise the risk of breast growth and tenderness but not breast cancer.

Different treatments for PCOS should be tailored to the individual, including lifestyle changes and various medications.

Diagnosing and treating PCOS is complex due to differing criteria and requires a team approach.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Testosterone replacement is recommended for men with low testosterone levels and symptoms of hypogonadism.

Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.

Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.

More research is needed to understand how testosterone is maintained in adult males.

The chapter explains the causes of excessive hair growth and masculinization in women and how to measure hormone levels related to these conditions.

Combining flutamide and finasteride can reduce prostate weight and tumor growth, potentially benefiting treatments needing optimal DHT inhibition.

Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.

Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

High testosterone levels in 20% of the women studied may indicate PCOS, while 80% had low levels with potential health impacts.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

Intradermal injections improve hair density and thickness better, while derma roller is more convenient.

Eating alfalfa sprouts every day can raise testosterone levels in middle-aged men, but broccoli sprouts don't have this effect.

High aldosterone and free testosterone levels link to female hair loss; testing aldosterone may predict hypertension risk.

Men with male pattern baldness had higher body fat and obesity-related measurements but similar heart fat and artery thickness compared to healthy men.

SHBG binding properties are unchanged in male liver cirrhosis patients.

Women with AGA have more androstenedione and dihydrotestosterone, less copper and zinc; copper imbalance affects AGA; treatment improves hormones and minerals.

Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.

Nanoemulgel improves hair growth and quality using finasteride without irritation.

The document concludes that accurate diagnosis and management of PCOS are crucial due to its associated health risks.

Testosterone treatment for older men can have short-term benefits, but long-term risks are unclear, requiring careful evaluation and monitoring.

Men with low testosterone should be carefully evaluated and monitored before and during treatment.