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Trichohyalin is modified by enzymes to form strong structures in hair cells.

S100A3 protein is crucial for hair shaft formation in mice.

Lack of Cisd2 disrupts calcium balance in cells, leading to poorly functioning neutrophils.

Mouse profilaggrin helps in skin cell differentiation and may be involved in calcium signaling.

A bald man grew hair on his head after taking a drug called diazoxide, but lost it again when he stopped the medication.

Dutasteride may help reduce brain plaque linked to Alzheimer's by affecting cell energy structures and waste removal.

Understanding drug interactions, side effects, and patient-specific factors is crucial for effective dermatological care.

Potassium channel openers help form elastic fibers in arteries and can treat elastin deficiency and hypertension.

Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.

Changing protein kinase levels in pituitary cells affects calcium flow and beta-endorphin release.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.

Cobalt is important for health but too much or too little can cause health problems, and its environmental buildup is a concern.

Higher hair calcium to magnesium ratios and lower chromium levels in hair may indicate insulin resistance in Korean men.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

6-Gingerol from ginger may slow down hair growth by affecting certain enzymes and growth factors.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.

Genes related to calcium signaling and lipid metabolism are important for curly hair in Mangalitza pigs.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Enzymes that change arginine to citrulline are important for skin barrier and hair formation, and their malfunction can lead to skin conditions and hair disorders.

Enzymes called PADIs play a key role in hair growth and loss.

Understanding keratinization is crucial for treating skin conditions like ichthyoses and psoriasis.

Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.

Sex steroids produced in the hippocampus are crucial for brain functions like memory and learning in rodents.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.

Understanding skin structure and development helps diagnose and treat skin disorders.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.