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In this study on a mouse model of vitiligo, NB-UVB/ADSC combination therapy improved oxidative stress and calcium homeostasis, but the protective effect was reversed by inhibiting Nr2 signaling.

NFATc1 is crucial for keeping hair follicle stem cells inactive.

Fibroblast bioelectric signaling can promote hair growth and may help treat hair loss.

This case report describes a rare instance of pediatric idiopathic hypoparathyroidism in an 11-year-old Saudi boy, characterized by extensive cranial calcifications beyond the basal ganglia, with no other neurological abnormalities.

This study suggests that hair loss was a metabolic adaptation allowing hominids to evolve larger brains by alleviating dietary restrictions on essential amino acids for hair and brain development.

This study reviews the complex keratinization process in the epidermis, detailing how various factors regulate keratinocyte differentiation and emphasizing the importance of understanding this process for the pathogenesis of skin disorders like ichthyoses and psoriasis.

This review discusses current knowledge about the TRPV3 ion channel's role in skin functions and diseases, highlighting its potential as a therapeutic target for pain and itch, though suitable ligands are limited.

In this study, researchers observed that fasting-induced molting in laying hens led to increased thyroid hormones, which may regulate feather molting by affecting hair follicle growth through specific signaling pathways, highlighting molecular changes during induced molting.

This study found that adding keratin to a collagen hydrogel improved keratinocyte differentiation compared to a pure collagen hydrogel, particularly when calcium was also present in the media.

In this study, researchers used SEM/SDD-EDS to identify waterborne minerals like calcium and aluminum in the scalp hair cuticle of individuals using treated or untreated water for hair washing, finding that prior application of coconut oil or conditioners can prevent calcium uptake.

This study discovered that calcium dependent protein kinase 1 (CPK1) directly activates cyclic nucleotide-gated channels 5, 6, and 9, promoting root hair growth in Arabidopsis by regulating Ca²⁺ signaling.

This review discusses the genetic causes and pathogenesis of Olmsted syndrome, emphasizing the potential for a genotype-phenotype correlation due to TRPV3 mutations, and explores avenues for individualized treatment developments for this condition.

This review highlights the crucial role of vitamin D signaling in epidermal stem cells during skin wound healing, emphasizing its distinct functions from calcium metabolism and its importance in genomic regulation mediated by the vitamin D receptor.

In this study, researchers used proteomic and metabolomic analyses to explore hair follicle development in embryonic cashmere goats, identifying significant roles for the oxytocin signalling pathway and associated networks in this process.

This review discusses the formation of gintonin LPAs in ginseng during processing and reports no new clinical results; the authors suggest potential benefits against degenerative diseases through LPA receptors.

This article reviews methods for examining the localization and activity of ROP GTPase, cortical microtubule organization, and F-actin dynamics in plant cell models, but reports no new experimental results.

This review discusses the role of mineral nutrients in human health, emphasizing the importance of dietary sources and education to prevent mineral deficiencies, and reports no new clinical results.

This meta-analysis reported no significant improvement in muscle strength or mobility with glucocorticoid treatment for progressive muscular dystrophy but observed an increase in adverse effects like acne and emotional irritability.

This article discusses the composition and benefits of multivitamin gummies, emphasizing their palatability and potential health effects, but reports no new clinical findings.

This study found that acute stress can cause rapid hair loss by triggering necrosis in hair follicle cells and initiating autoimmunity, revealing a mechanism where stress-induced nerve activity leads to tissue damage and immune system activation.

This review highlights that injectable biostimulatory agents like poly-L-lactic acid, polycaprolactone, and calcium hydroxyapatite are effective in regenerative aesthetics by enhancing collagen production, stimulating adipogenesis, and improving dermal quality, although further research is needed to standardize protocols and confirm long-term safety and efficacy.

This study found that humanized mouse models expressing mutated or reduced levels of the vitamin D receptor were able to maintain normal mineral homeostasis and prevent typical symptoms of vitamin D resistance.

This study found that among older men, low levels of free dihydrotestosterone were associated with an increased risk of developing atrial fibrillation.

This study found that expanding hair follicle keratinocytes with a fibroblast feeder followed by short-term coculture with dermal papilla cells could restore their ability to form new hair follicles.

This study found that vitamin D receptor expression is associated with proliferating keratinocytes, while retinoid X receptor α is linked to differentiating keratinocytes, suggesting differential targeting by vitamin D metabolites.

This study found that among older men, lower calculated free testosterone was significantly associated with a higher risk of heart failure, suggesting a possible role of testosterone deficiency in heart failure incidence.

In this study, researchers identified a novel p.R50X mutation in the vitamin D receptor gene, linked to hereditary vitamin D-resistant rickets in two siblings.

This review discusses the controversial cardiovascular safety and efficacy of subcutaneous testosterone therapy in postmenopausal women, noting that its long-term use appears safe, but CV risk assessments remain disputed.

This study utilized EDAR gene-targeted cashmere goats to identify 732 differentially expressed genes and 140 proteins associated with abnormal hair growth, providing insights into the regulatory mechanisms of cashmere follicle development.

This study found that the opioid system, particularly via the delta opioid receptor, broadly regulates cutaneous mechanosensation, including touch, and suggests targeting this receptor could alleviate injury-induced mechanical hypersensitivity.