June 2024 in “CRC Press eBooks” This chapter reviews recent advances in understanding how calcium uptake and signaling in plant roots influence growth, defense, and symbiosis, highlighting the complex molecular networks involved and the extensive systems still to be explored.
April 2024 in “BMB Reports” This study used Cisd2 knockout mice models and found that these mice display premature aging characteristics and an increase in dysfunctional neutrophils, suggesting Cisd2's role in calcium homeostasis and neutrophil function via interactions with Calnexin and SERCA.
April 2024 in “Archives of toxicology” Certain substances can protect against ear damage from some antibiotics in zebrafish.
CaBP1 and 2 are necessary for maintaining calcium currents and hearing in inner ear cells.
CaBP1 and CaBP2 are important for continuous hearing by preventing inactivation of calcium currents in ear cells, with CaBP2 also able to restore hearing when reintroduced.
CaBP1 and CaBP2 are necessary for proper hearing and neurotransmission in the ear's inner hair cells.
CaBP1 and CaBP2 are important for maintaining hearing by supporting continuous calcium currents and nerve signaling in the ear.
January 2024 in “Bratislavské lekárske listy/Bratislava medical journal” This study examined the vasorelaxant effects of two similar alkaloids, chloroquine and cinchonine, in a model of smooth muscle contractions induced by phenylephrine. Results are not reported in the abstract.
January 2024 in “Universidad Peruana Cayetano Heredia Institutional Repository” In this in vitro study, simple centrifugation with calcium gluconate activation led to a significantly higher release of PDGF-BB in PRP compared to other methods, which may inform improved clinical PRP preparation protocols.
December 2023 in “Sains Malaysiana” In this study, researchers used in silico mutagenesis to identify key calcium-binding sites influencing the stability of Rand protease from Bacillus subtilis, potentially enhancing its application in industries like leather dehairing by improving stability and eliminating the need for additional metal ions during the process.
June 2023 in “Frontiers in Genetics” This study suggests that the curly hair phenotype in Mangalitza pigs may involve complex gene interactions related to calcium signaling and lipid metabolism, rather than changes in TRPM2 or CYP4F3 expression.
May 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, researchers found that the expression of SLC1A6, a gene linked to calcium gradient and keratinocyte differentiation in the skin, significantly decreases with age, which may contribute to reduced skin barrier function in elderly individuals.
This study found that dermoscopy combined with calcium fluorescent white staining effectively aided in the early diagnosis and treatment evaluation of tinea capitis by highlighting specific hair changes and fluorescent patterns associated with different dermatophyte infections in a sample of 20 patients.
June 2020 in “Acta Scientific Otolaryngology” This case study presents a patient with male-pattern alopecia who received PRP treatment with calcium chloride after ruling out other potential causes.
July 2019 in “Ferroelectrics” The researchers reported that increasing protein content in human hair keratin/calcium alginate blend films led to larger molecular aggregates, which influenced the films' physical properties such as light transmittance and tensile strength.
April 2019 in “Journal of Investigative Dermatology” This study found that bioelectric and biochemical signaling mechanisms coordinate collective cell movement during chicken feather bud morphogenesis, suggesting a potential new angle for research in skin development and wound healing.
April 2018 in “Journal of Investigative Dermatology” This study demonstrated that in genetic mouse models, the calcium sensor Stim1, not Stim2, is essential for sweat secretion in sweat glands.
This case report identified trichorrhexis nodosa in a patient, likely due to the topical use of an ayurvedic preparation containing calcium hydronide.
May 2015 in “Immunology Endocrine & Metabolic Agents - Medicinal Chemistry” This study suggests that vitamin D and calcium signaling are crucial for normal wound healing, with deficiencies in these pathways potentially delaying recovery due to diminished stem cell activity and response.
June 2010 in “Journal of Veterinary Clinics” This study established an experimental model to visualize calcium ion distribution after skin barrier damage in canine epidermis, observing that calcium gradients changed differently depending on the type of damage and time elapsed.
Hair can show daily calcium changes, linked to body calcium levels and influenced by hormones, and can help assess calcium metabolism issues.
This study concluded that a combination of millet seed extract, L-cystine, and calcium pantothenate may improve anagen hair rate in women with androgenetic alopecia over six months.
August 1994 in “Molecular Endocrinology” This study found that AtT-20 pituitary cells with higher cAMP-dependent kinase activity had larger calcium currents and significantly increased beta-endorphin release compared to cells with lower kinase activity.
This study demonstrates that the trichohyalin gene is located at chromosomal region 1q21, where several other genes related to epidermal differentiation also map.
October 1990 in “Pediatric Research” This case report details a severe instance of VDR-II where intravenous calcium infusions, administered nightly, successfully improved clinical, radiological, and biochemical signs of rickets without alopecia despite ineffective calcitriol therapy.
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December 1984 in “Journal of the American Geriatrics Society” This study found that serum and hair mineral concentrations, including copper and zinc, showed no differences between Alzheimer's patients and their healthy spouses, suggesting no diagnostic utility for Alzheimer's disease.
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June 2005 in “British Journal of Dermatology” Calretinin identifies the companion cell layer in human hair follicles.
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August 1987 in “Archives of Dermatology” This communication reports previously unreported side effects, severe bullous dermatosis and onycholysis, in three patients undergoing high-dose methotrexate and leucovorin calcium therapy, impacting their chemotherapy schedules.
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December 2016 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics” This study found that multiple ion channel modulators, used here at clinical concentrations, increased intracellular calcium release in prostate and breast cancer cell lines.
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June 2013 in “International Journal for Vitamin and Nutrition Research” This study found that higher hair calcium concentration was associated with lower calcium intake and bone mineral density among women over 20 years old in Korea.