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New compounds similar to cromakalim were less effective at inhibiting insulin release but improved in solubility and one acted as a calcium entry blocker, not a potassium channel opener.

SHBG may be a useful early indicator and treatment target for PCOS.

Certain drugs increase calcium levels in cancer cells by triggering internal calcium release.

Hair proteins have weak spots in their α-helical segments.

pH, calcium, and reactive oxygen species regulate plant cell growth, with key roles for NADPH oxidases and plasma membrane H+-ATPases.

Long-term use of seizure medications can disrupt calcium metabolism, but this can be treated with vitamin D or UV light and does not affect seizure control.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Inhibiting ALOX12 can help hair cuticle maturation by increasing S100A3 citrullination.

A boy with severe Vitamin D-resistant rickets did not respond to treatment and lacked a common symptom, suggesting a need for alternative treatments.

GRHL3 is important for controlling gene activity in skin cells during different stages of their development.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Key genes can rewire networks, changing skin appendage types.

The R343H mutation in the VDR gene causes vitamin D-resistant rickets with alopecia by impairing specific gene activity.

Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.

TRPV4 helps cells repair tissue and reduce scarring by controlling calcium levels.

Genes related to calcium signaling and lipid metabolism are important for curly hair in Mangalitza pigs.

The gene Prss53 affects hair shape and bone development in rabbits.

Water quality affects mineral content in hair, and coconut oil can protect against damage.

Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.

Mefloquine, an antimalarial drug, is effective in killing melanoma cells resistant to other treatments by causing lethal stress in the cells.

The TGM3 gene's promoter region is key for skin and hair cell function and may aid gene therapy.

Researchers created a mouse model of a type of rickets that does not cause hair loss.

Astilbin can potentially calm overactive immune responses, like in Type 1 Diabetes, by suppressing certain cell activities and reducing inflammation.

Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Researchers found a gene in hamsters that responds to male hormones and may be indirectly controlled by them.

Pranlukast and mirabegron may work as new diabetes drugs.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.