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Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.

Calcium affects where root hairs grow, but other unknown factors determine their growth direction.

New treatments for hair loss may target specific pathways and generate new hair follicles.

Mutations in three genes cause Uncombable Hair Syndrome, leading to frizzy hair that can't be combed flat.

Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.

Patients with the same genetic mutation for vitamin D-resistant rickets showed different symptoms but all improved with treatment except for hair loss.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Finasteride may cause kidney damage.

Procyanidins from grape seeds reduce nerve pain by blocking specific proteins and inflammation.

Men and premenopausal women in Korea show different patterns in iron and vitamin D levels, with no clear pattern for postmenopausal women.

VDR regulation varies by tissue and is crucial for its biological functions.

Trichohyalin is modified by enzymes to form strong structures in hair cells.

Four-amino acid part makes enzyme sensitive to finasteride.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.

Alopecia Areata is an autoimmune hair loss condition that needs more research for better treatments.

RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.

Finding functions for unknown GPCRs is hard but key for making new drugs.

The document explains how male reproductive hormones work and affect the body.

Thyroid disease can cause hair loss and treating thyroid problems might help with hair disorders.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

Myrtle has various health benefits and potential for medicine development.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.