1 citations
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May 2023 in “Cureus” In this case report, a rare instance of pilomatrixoma was identified in the left hand of a 40-year-old patient, with successful surgical treatment and no recurrence observed after four years of follow-up.
September 2025 in “Journal of Ayurveda and Integrated Medical Sciences” This study described trichilemmal cysts, firm lumps that form from blocked hair follicles, typically found on the scalp but also less commonly on other body parts, affecting less than 10% of the population and possibly inherited as an autosomal dominant trait.
This case report describes a rare instance of pilomatricoma, a benign tumor of the hair follicle, accompanied by striae distensae on a young man's flank, emphasizing the uniqueness of this presentation for timely diagnosis and care due to its potential for malignant transformation.
September 2016 in “Journal of Dermatological Science” This case report describes the first documented instance of epidermal nevus syndrome caused by a postzygotic KRAS G12C mutation in a three-year-old Japanese girl.
September 2016 in “Journal of Dermatological Science” This study found that P. cornucopiae extract showed antioxidant and protective effects on human skin fibroblasts, suggesting its potential as an antiaging agent by preventing oxidative stress-induced collagen breakdown.
February 2006 in “Journal of The American Academy of Dermatology” Terbinafine is more effective than itraconazole for toenail fungus, especially in older patients, and debridement improves its effectiveness.
September 2016 in “Journal of Dermatological Science” This study found that epidermal-specific deletion of aPKCλ in mice disrupted hair follicle stem cell quiescence and regeneration, leading to abnormal hair cycling and skin changes.
4 citations
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September 2011 in “Expert Review of Dermatology” This review discusses various treatment options for alopecia areata, noting a lack of consensus on grading and treatment algorithms, and reports no new clinical results.
11 citations
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January 1957 in “Journal of Histochemistry & Cytochemistry” This study demonstrated radiocalcium uptake in skin, eye, cartilage, and mucous glands, with the highest concentration in the hair follicle's keratogenous zone.
The authors of this study concluded that higher calcium levels in hair may indicate early metabolic changes leading to osteopenia or osteoporosis in menopausal women, even before detectable by standard DEXA imaging.
815 citations
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April 2010 in “The Journal of Clinical Endocrinology & Metabolism” This review examines the relationship between polycystic ovary syndrome and cardiovascular disease risk, but reports no new clinical findings; the panel calls for guidelines to prevent CVD in this population.
271 citations
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September 2008 in “Nutrition reviews” This study identified new dietary ligands for the human vitamin D receptor, including curcumin and gamma-tocotrienol, which may influence its biological functions.
237 citations
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February 2016 in “Science Translational Medicine” This study found that many effects previously thought to be caused by circadian rhythm disruption in Bmal1 knockout mice are actually due to BMAL1's properties unrelated to its clock function.
220 citations
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March 2020 in “Advanced functional materials” This review discusses the mechanisms and potential therapeutic benefits of mesenchymal stromal cell-derived extracellular vesicles delivered via biomaterials, but reports no new clinical results.
220 citations
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August 1988 in “Clinical endocrinology” This review provides a comprehensive overview of melatonin's physiological roles, effects, and clinical implications, but it does not present new experimental findings.
174 citations
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April 2005 in “The American journal of pathology (Print)” This study found that TRPV1 activation in human scalp hair follicles inhibited hair shaft elongation, suppressed proliferation, and induced apoptosis, suggesting TRPV1 as a potential target for managing hair growth and epithelial disorders.
166 citations
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April 2012 in “Journal of The American Academy of Dermatology” This study reviewed clinical data from 60 patients with frontal fibrosing alopecia and found increasing prevalence and generally poor response to treatment, with the cause remaining unclear.
101 citations
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January 1997 in “Journal of Investigative Dermatology Symposium Proceedings” This review discusses neural mechanisms involved in hair growth control, focusing on piloneural interactions, but reports no clinical findings; the authors suggest further exploration for managing hair growth disorders.
65 citations
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January 2013 in “Cochrane library” This review found that infliximab, golimumab, and some forms of radiotherapy significantly improved nail psoriasis compared to controls, although they could have serious adverse effects and are not commonly used specifically for nail issues.
62 citations
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January 2013 in “Skin Pharmacology and Physiology” This study found that low serum ferritin and vitamin D2 levels are associated with hair loss in females with chronic telogen effluvium and female pattern hair loss, suggesting potential benefits of screening and supplementation.
58 citations
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November 2012 in “PLoS ONE” This study found that dermal fibroblast cultures, especially those with higher alpha-smooth muscle actin expression, can be used to produce skin-derived precursor cells, unlike human hair follicle dermal papilla cultures.
56 citations
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July 2008 in “European journal of endocrinology” This study found that a 6-month treatment with either metformin or rosiglitazone significantly improved endothelial function in young women with PCOS without any one drug being superior.
54 citations
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October 2024 in “Nature Communications” In this study, researchers developed a method to control the valence states of Mo in nanozymes, optimizing their activity for ROS-related therapies, particularly acute kidney injury treatment, and enabling real-time monitoring with photoacoustic imaging.
40 citations
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September 2003 in “Archives of Dermatology” This webpage provides access options for JAMA Dermatology but does not contain research findings or results.
39 citations
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November 2015 in “Pediatric Nephrology” In this study, rituximab treatment for children with steroid-dependent nephrotic syndrome was associated with a longer remission time and fewer side effects compared to cyclophosphamide.
33 citations
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January 2011 in “Elsevier eBooks” This article reviews the complexity and diverse manifestations of systemic lupus erythematosus, highlighting potential genetic, hormonal, and environmental factors in its pathogenesis without presenting new clinical findings.
29 citations
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March 2015 in “Journal of Investigative Dermatology” This study provides evidence that Cyclosporine A inhibits catagen development in human hair follicles, suggesting different underlying mechanisms from those observed in rodent studies.
26 citations
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October 2017 in “Clinical Reviews in Allergy & Immunology” This review explores skin manifestations associated with autoimmune liver diseases and highlights known and probable links, such as vitiligo's strong association with autoimmune hepatitis.
24 citations
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April 2017 in “Aesthetic plastic surgery” In this study, micro-autologous fat transplantation (MAFT) for frontal augmentation using the MAFT-GUN showed high patient satisfaction and no complications among 178 patients, suggesting it may be a reliable method for forehead contouring.
24 citations
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November 1992 in “Journal of the American Academy of Dermatology” This report on a case of cutaneous lymphomatoid granulomatosis underscores the pivotal role dermatologists have in its early diagnosis, which could potentially improve the otherwise poor prognosis.